Kuangyn Yen | Gene Regulation and Epigenetics | Best Researcher Award

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Dr. Kuangyn Yen | Gene Regulation and Epigenetics | Best Researcher Award

Chinese Academy of Medical Sciences and Peking Union Medical College | China 

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📘 KUANGYU YEN, PhD: PIONEER IN TRANSCRIPTION REGULATION AND CHROMATIN DYNAMICS

🎓 EARLY ACADEMIC PURSUITS

Kuangyu Yen's academic journey began at National Taiwan University, where he earned a Bachelor of Science in Horticulture (Molecular Biology Unit) in 1998. His passion for molecular biology led him to pursue advanced degrees at the University of Manchester, UK, where he completed both an MRes (2001) and a Ph.D. in Molecular Biology (2005). His doctoral research laid the foundation for his expertise in transcription regulation, setting the stage for his future research endeavors.

💼 PROFESSIONAL ENDEAVORS

Dr. Yen's professional career is marked by a blend of international experiences and prestigious appointments:

  • Chinese Academy of Medical Sciences & Peking Union Medical College (2022-present): Researcher.
  • Southern Medical University (2014-2022): Professor, where he contributed significantly to the academic and research community in Guangzhou, China.
  • Pennsylvania State University (2008-2014): Post-doctoral fellow and later Research Assistant Professor, expanding his expertise in transcription regulation and chromatin dynamics.
  • University of Washington (2005-2007): Post-doctoral fellow, further deepening his understanding of molecular biology at the intersection of chromatin and transcription.
  • National Taiwan University (1998-2000): Research Assistant, where his scientific curiosity began to flourish.

🔬 CONTRIBUTIONS AND RESEARCH FOCUS ON GENE REGULATION AND EPIGENETICS

Dr. Yen's research focus is on transcription regulation and its influence on cell fate determination, particularly through chromatin dynamics. His innovative use of bioinformatic tools, CRISPR/Cas9-engineered depletion, and biochemical reconstitution has made him a leader in understanding how chromatin regulates transcription in a spatiotemporal manner. His research has significant implications for disease diagnosis and treatment, especially in preventing precancerous cells from progressing into cancer cells. One of his notable contributions is the development of a two-tipping point model, which helps explain how cell fate transitions. This model has potential applications in both basic research and clinical practice, offering insights into the molecular mechanisms of various diseases.

🌍 IMPACT AND INFLUENCE

Dr. Yen’s work has been internationally recognized, and he has secured multiple high-profile grants and awards, such as the Thousand Youth Talents Award and the Outstanding Youth Award. His research has attracted funding from the National Natural Science Foundation of China, the National Key Research and Development Program of China, and international collaborations such as the France-China Joint Research Projects Program. His influence extends to key speaking engagements and workshops in the field of epigenetics and hematopoiesis at global institutions, including John Hopkins University.

📊 ACADEMIC CITATIONS

With several publications to his name, Dr. Yen’s work is well-cited in the scientific community, reinforcing his status as an influential researcher in molecular biology. His contributions to understanding transcription regulation and chromatin dynamics continue to resonate, particularly in the areas of epigenetics and hematopoiesis.

🌟 LEGACY AND FUTURE CONTRIBUTIONS

Kuangyu Yen’s legacy will likely center on his pioneering research into how chromatin structure affects transcriptional regulation and cell fate transitions. His use of cutting-edge tools like CRISPR/Cas9 and bioinformatics has laid the groundwork for future advancements in cancer prevention and molecular diagnostics. Moving forward, Dr. Yen’s ongoing research at the Chinese Academy of Medical Sciences is poised to further influence how scientists understand and manipulate transcription regulation. His editorial role at Communication Biology (2024-2026) and other professional activities suggest that his contributions to the field are far from over.

🚀 AWARDS AND PROFESSIONAL RECOGNITION

  • National Natural Science Foundation of China: Multiple grants for outstanding research, totaling over 500,000 USD.
  • Thousand Youth Talents Award: A prestigious recognition with funding of 0.67 million USD.
  • Numerous invited talks at top-tier institutions and international conferences.

Kuangyu Yen’s continuous dedication to his research and the academic community positions him as a transformative figure in molecular biology, with future contributions set to further shape the field.

📅 FUTURE HIGHLIGHTS

Dr. Yen’s ongoing projects and his active engagement with the scientific community, including participation in international editorial boards and professional panels, indicate that his work will continue to shape the future of molecular biology research for years to come.

📑NOTABLE PUBLICATIONS 

"RUNX1 Upregulates CENPE to Promote Leukemic Cell Proliferation" 

  • Authors: Liu, S., Yang, J., Sun, G., Yen, K., & Lu, T. (2021).
  • Journal: Molecular Biosciences
  • Year: 2021

"Chemical screening reveals Ronidazole is a superior prodrug to Metronidazole for nitroreductase-induced cell ablation system in zebrafish larvae" 

  • Authors: Lai, S., Kumari, A., Liu, J., Yen, K., & Xu, J.
  • Journal: Genetics and Genomics
  • Year: 2021

"Comprehensive understanding of Tn5 insertion preference improves transcription regulatory element identification"

  • Authors: Zhang, H., Lu, T., Liu, S., Chen, F., & Yen, K.
  • Journal: NAR Genomics and Bioinformatics
  • Year: 2021

"Functional Verification of Novel ELMO1 Variants by Live Imaging in Zebrafish"

  • Authors: Xue, R., Wang, Y., Wang, T., Liu, Q., & Xu, J.
  • Journal: Frontiers in Cell and Developmental Biology
  • Year: 2021

"SPI1-KLF1/LYL1 axis regulates lineage commitment during endothelial-to-hematopoietic transition from human pluripotent stem cells"

  • Authors: Qu, K., Mo, S., Huang, J., Shen, J., & Yen, K.
  • Journal: iScience
  • Year: 2024

Flavio Faletra | Cardiovascular Genetics and Genomics | Best Researcher Award 

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Dr. Flavio Faletra | Cardiovascular Genetics and Genomics | Best Researcher Award 

University Health Authority of Central Friuli | Italy

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Biography of Flavio Faletra: A Leader in Medical Genetics 🧬

EARLY ACADEMIC PURSUITS 🎓

Flavio Faletra began his distinguished academic journey at the University of Trieste, where he earned a Degree in Medicine and Surgery in 2005. He further specialized in Medical Genetics at the same institution, completing his specialization in 2009. Demonstrating a strong commitment to his field, Faletra pursued advanced education with a Second-level Master’s degree in Clinical Genetics from the University of Siena in 2011. His foundational academic achievements laid the groundwork for a career focused on the intersection of genetics and clinical medicine.

PROFESSIONAL ENDEAVORS 🏥

Flavio Faletra has held multiple pivotal roles in medical genetics. Since August 2023, he has been an Expert in Genetics at the Regional Health Coordination Agency (ARCS) in Friuli Venezia Giulia, Italy. Alongside his expert role, he has been a University Lecturer on contract at the University of Trieste from 2018 to 2023, contributing to the academic growth of students in the field of genetics. His professional journey includes numerous positions as a Medical Director I Level in Medical Genetics, starting with the IRCCS Burlo Garofolo (2013–2017) and progressing through roles in University Health Authority Friuli Centrale and IRCCS Burlo Garofolo until his current position, reflecting his leadership in the medical genetics field.

CONTRIBUTIONS AND RESEARCH FOCUS ON CARDIOVASCULAR GENETICS AND GENOMICS  🔬

Faletra’s research focus spans various critical areas of medical genetics, from pediatric endocrinology to rare genetic diseases. He has contributed extensively to genetic counseling and clinical genetics, with a strong emphasis on pediatric genetic disorders. His work as a Thesis Co-Surveyor and PhD Supervisor at the University of Trieste demonstrates his dedication to nurturing the next generation of geneticists. Through courses such as the Genetic Consulting in Medical Genetics Specialization School, he has shaped the landscape of medical genetics education. His involvement in pediatric endocrinology through ADE courses has brought syndromic genetic disorders to the forefront, significantly impacting the medical community’s approach to these conditions.

IMPACT AND INFLUENCE 🌍

Faletra’s influence extends beyond academia into clinical practice, where his expertise has helped shape genetic diagnostic strategies across Italy. His participation in national conferences, such as the National Congress of Human Genetics and seminars on genetic syndromes and diagnostics, marks him as a key figure in Italian medical genetics. Faletra's teaching and research efforts have particularly impacted the areas of growth retardation, fetal malformations, and syndromic genetic disorders, positioning him as a central figure in advancing genetic medicine in pediatrics.

ACADEMIC CITES 📚

Flavio Faletra's work has been cited in numerous academic publications, with topics ranging from genetic diagnostic methods to therapeutic approaches for rare genetic disorders. His research in exome sequencing and next-generation sequencing techniques has had a broad impact, being referenced widely in the fields of human genetics and pediatric medicine.

LEGACY AND FUTURE CONTRIBUTIONS 🏅

Faletra’s legacy lies in his dedication to medical genetics, particularly in the areas of pediatric syndromic diseases and clinical genetics. His contribution to education, research, and clinical practice has left an indelible mark on the field. Looking ahead, his ongoing role as an expert and lecturer promises continued contributions to genomic medicine and the advancement of personalized treatment for genetic disorders. Through his continuous involvement in research, teaching, and clinical practice, Faletra remains at the forefront of innovation in medical genetics, with the potential to further revolutionize the diagnosis and treatment of complex genetic diseases.

NOTABLE PUBLICATIONS 📑

"SRSF1 haploinsufficiency is responsible for a syndromic developmental disorder associated with intellectual disability" 

  • Authors: Bogaert, E., Garde, A., Gautier, T., Dermaut, B., Vitobello, A.
  • Journal: American Journal of Human Genetics
  • Year: 2023

"Haploinsufficiency as a Foreground Pathomechanism of Poirer-Bienvenu Syndrome and Novel Insights Underlying the Phenotypic Continuum of CSNK2B-Associated Disorders" 

  • Authors:Di Stazio, M., Zanus, C., Faletra, F., d’Adamo, A.P., Musante, L.
  • Journal: Genes
  • Year: 2023

"A new neurodevelopmental disorder linked to heterozygous variants in UNC79"

  • Authors: A., Liu, Z., Luo, S., Liao, W., & Ren, D.
  • Journal: Genetics in Medicine
  • Year: 2023

"The clinical impact of the first-trimester nuchal translucency between the 95th–99th percentiles"

  • Authors: Fantasia, I., Catagini, S., Zamagni, G., Feresin, A., & Stampalija, T.
  • Journal: Prenatal Diagnosis
  • Year: 2023

"A bird’s eye view on the use of whole exome sequencing in rare congenital ophthalmic diseases"

  • Authors: Zucco, J., Baldan, F., Allegri, L., Damante, G., Mio, C.
  • Journal: Journal of Human Genetics
  • Year: 2024

Gang liu | Cancer | Best Researcher Award

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Prof Gang liu | Cancer | Best Researcher Award

Gansu Provincial Center for Disease Control and Prevention | China

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Gang Liu: Pioneer in Radiobiology and Preventive Medicine ⚛️

EARLY ACADEMIC PURSUITS 🎓

Gang Liu began his academic journey at Lanzhou University, where he pursued a PhD in preventive medicine. His graduation in 1997 marked the beginning of a career dedicated to understanding the impacts of radiation on health. His academic training in preventive medicine provided the foundation for his future contributions to radiobiology and public health, particularly in the context of disease control and prevention.

PROFESSIONAL ENDEAVORS 🏢

After obtaining his PhD, Gang Liu embarked on a distinguished career at the Gansu Provincial Center for Disease Control and Prevention. His professional focus has been on the intersection of radiobiology, immunology, and tumor screening. In 2019, his registration as a health physicist signaled a significant milestone. He became the technical lead for a groundbreaking study on low-dose dose-effect relationships, a critical area in radiation therapy and safety. His expertise in radiation protection and therapy has earned him a prominent position within the medical research community.

CONTRIBUTIONS AND RESEARCH FOCUS ON CANCER🧬

Gang Liu's research primarily revolves around radiobiology and radiation protection in therapy. His technological advancements in biological dose estimation are considered cutting-edge within China and recognized internationally. One of his significant contributions was revising the 2011 IAEA Manual based on findings from his studies on radiological sensitivity and dose rates. This revision, coupled with his publications in the FASEB Journal, has made Liu a leading figure in radiation science. His work in chromosomal aberration analysis and developing noninvasive techniques for early-stage cancer screening underscores his innovative approach to medical research.

IMPACT AND INFLUENCE 🌍

Gang Liu's influence extends beyond national borders. His research on radiological sensitivity and dose rates, especially in the context of cancer screening and radiation therapy, has set new benchmarks in the field. The international recognition of his work, particularly his advancements in biological dose estimation and contributions to global radiation protection protocols, underscores his importance in radiobiology. His work is used by institutions worldwide to improve radiation safety standards and enhance cancer diagnostic techniques.

ACADEMIC CITATIONS 📚

His pioneering research has been published in prestigious journals such as the FASEB Journal, one of the top international platforms for scientific contributions. The citations of his work in radiological sensitivity, chromosomal aberration analysis, and cancer screening techniques reflect his deep impact on the scientific community, with his methods influencing both practical applications in healthcare and further research.

LEGACY AND FUTURE CONTRIBUTIONS 🔬

Gang Liu’s legacy will likely be defined by his leadership in advancing radiation protection technology and cancer screening techniques. As an innovator in radiological health, his influence will continue to grow through future contributions to radiation therapy safety, noninvasive cancer detection, and international health standards. His ongoing work in exploring new methods for biological dose estimation will further establish his standing as a key figure in the evolution of radiation medicine.

NOTABLE PUBLICATIONS 📑

"Study of Low-Dose Radiation Workers Ionizing Radiation Sensitivity Index and Radiation Dose-Effect Relationship" 

  • Authors: Liu, G., Zhang, R., Li, Y., Liu, Y.Y., Zhang, X.
  • Journal: Health Physics
  • Year: 2022

"Revision of cytogenetic dosimetry in the IAEA manual 2011 based on data about radio-sensitivity and dose-rate findings contributing" 

  • Authors:Liu, G.
  • Journal: FASEB Journal
  • Year: 2022

"Thyroid dose assessments due to inhalation of 131I for nuclear medicine workers"

  • Authors: Liu, G., Li, Y., Zhang, H., Niu, L.M., Zhang, R.
  • Journal: Frontiers in Public Health
  • Year: 2022

"Study of Indicators for Early and Rapid Diagnosis of Radiation Injury Is the Most Important in Patients With Cancer During Radiotherapy"

  • Authors: Liu, G., Niu, L.-M., Wang, L.-Q., Liu, Y.-Y., Zhang, R.
  • Journal: Dose-Response
  • Year: 2020

"Chromosomal aberration analysis: Novel noninvasive techniques for early-stage cancer screening"

  • Authors: Liu, G.
  • Journal: Clinica Chimica Acta
  • Year: 2024

Prof Xiuyun Liu | Neuropsychiatric Disorders | Best Researcher Award

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Prof Xiuyun Liu | Neuropsychiatric Disorders | Best Researcher Award

Pharmaceutical School, Tianjin University | China

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Biography of Xiuyun Liu 🎓🧠

EARLY ACADEMIC PURSUITS 📚

Xiuyun Liu's academic journey is marked by a strong foundation in biomedical engineering, which she pursued at Tianjin University, China. She earned both her Bachelor’s and Master’s degrees from the College of Precision Instrument and Opto-electronics Engineering, showcasing her dedication to the intersection of engineering and medical science. Her academic excellence led her to the prestigious University of Cambridge in the UK, where she completed her Ph.D. in Clinical Neurosciences at Newnham College. Supported by the highly competitive Gates Scholarship, her research focused on groundbreaking areas within neurosciences, laying the foundation for her future contributions to medical research.

PROFESSIONAL ENDEAVORS 🏢

Dr. Liu's professional career is as impressive as her academic background. She began as a Postdoctoral Researcher in the Department of Physiological Nursing at the University of California, San Francisco. She then became a Research Fellow in the Department of Anesthesiology and Critical Care Medicine at Johns Hopkins University. These roles allowed her to deepen her research in critical care medicine and anesthesiology, contributing valuable insights to these fields. Currently, Dr. Liu serves as the Dean of the School of Pharmaceutical and Science Technology at Tianjin University, where she continues to influence the next generation of medical professionals.

CONTRIBUTIONS AND RESEARCH FOCUS ON NEUROPSYCHIATRIC DISORDERS🔬

Dr. Liu has made significant contributions to the field of neurocritical care and biomedical engineering. Her research focuses on the development of innovative technologies and methodologies in critical care and perioperative medicine. As the Executive Director of the National Neurocritical Medicine Innovation Center, she leads research initiatives that aim to revolutionize the management of neurological emergencies. Her work is also closely associated with the development of life support technologies, reflecting her deep commitment to improving patient outcomes in critical care settings.

IMPACT AND INFLUENCE 🌍

Dr. Liu's influence extends beyond her research. She holds key positions in various prestigious organizations, including being a member of the Research Committee of the Society of Critical Care Anesthesiologists (SOCCA) in the USA and the Vice President of the Life Support Technology Branch of the Chinese Medical Rescue Association. Her leadership in these roles underscores her impact on both national and international levels, shaping the future of critical care and anesthesiology.

ACADEMIC CITATIONS AND HONORS 🏆

Dr. Liu’s research has garnered significant attention, leading to numerous citations in academic journals and conferences. Her work has been recognized with multiple awards, including the MIT Innovators 35 Under 35 in 2023, the National Teaching Achievement Award, and the Outstanding Youth of Tianjin University. Additionally, she received the prestigious Bill Gates Scholarship during her time at Cambridge, a testament to her academic prowess and potential for future impact.

LEGACY AND FUTURE CONTRIBUTIONS 🌟

As a leading figure in neurocritical care and biomedical engineering, Dr. Liu's legacy is already being shaped by her contributions to medical research and education. Her future contributions are poised to continue influencing the fields of critical care, life support technology, and medical engineering. With her ongoing leadership roles and innovative research, Dr. Liu is set to leave a lasting impact on the global medical community, inspiring future generations of scientists and medical professionals.

NOTABLE PUBLICATIONS 📑

"Enhancing Motor Sequence Learning via Transcutaneous Auricular Vagus Nerve Stimulation (taVNS): An EEG Study" 

  • Authors: Chen, L., Tang, C., Wang, Z., Liu, X., Ming, D.
  • Journal: IEEE Journal of Biomedical and Health Informatics
  • Year: 2024

"Congenital hydrocephalus: a review of recent advances in genetic etiology and molecular mechanisms" 

  • Authors: Liu, X.-Y., Song, X., Czosnyka, M., Pang, M.-J., Ming, D.
  • Journal: Military Medical Research
  • Year: 2024

"Photoacoustic imaging in brain disorders: Current progress and clinical applications"

  • Authors: Liu, X., Li, H., Pang, M., Wu, Y., Ming, D.
  • Journal: VIEW
  • Year: 2024

"Heart-brain axis: low blood pressure during off-pump CABG surgery is associated with postoperative heart failure"

  • Authors: Liu, X.-Y., Mu, J.-J., Han, J.-G., Guo, Z.-G., Ming, D.
  • Journal: Military Medical Research
  • Year: 2024

"Molecular understanding of the therapeutic potential of melanin inhibiting natural products"

  • Authors: Pang, M., Xu, R., Xi, R., Liu, X., Ming, D.
  • Journal: RSC Medicinal Chemistry
  • Year: 2024

Havva Ortabozkoyun | Gene Regulation | Best Researcher Award

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Dr. Havva Ortabozkoyun | Gene Regulation | Best Researcher Award

University of Miami Miller School of Medical / Sylvester Cancer Center | United States

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🧬 Havva Ortabozkoyun-Kara, PhD: Pioneering Epigenetics and Cancer Biology Researcher

🧑‍🎓 EARLY ACADEMIC PURSUITS

Havva Ortabozkoyun-Kara, PhD, embarked on her academic journey with a Bachelor of Science in Molecular Biology and Genetics from Middle East Technical University (METU) in Ankara, Turkey. Graduating with a stellar GPA of 3.80/4.00 in 2010, she demonstrated early on her dedication to understanding complex biological systems. Her education continued at Utrecht University in the Netherlands, where she pursued a Master of Science in Cancer Genomics and Developmental Biology. With a perfect GPA of 4.00/4.00, she excelled in this program, setting a strong foundation for her future research in cancer biology. Dr. Ortabozkoyun-Kara then achieved her PhD in Stem Cell Biology from New York University (NYU), where she graduated with a GPA of 3.89/4.00. During her doctoral studies, she delved into stem cell and developmental biology, further refining her focus on the mechanisms that drive cellular diversity and disease processes.

🧑‍🔬 PROFESSIONAL ENDEAVORS

Dr. Ortabozkoyun-Kara’s professional journey is marked by her extensive research experience in some of the most prestigious laboratories in the world. She began as a rotation student in the lab of Iannis Aifantis at NYU, where she explored the role of the ubiquitin system in cancer and stem cell function. Her doctoral research, conducted in the lab of Danny Reinberg at NYU School of Medicine, involved pioneering work on the insulation function of CTCF and the characterization of Polycomb Repressive Complex (PRC1) during differentiation. After completing her PhD, she continued her research as a Postdoctoral Fellow in the Reinberg Lab, focusing on gene regulation and the role of MAZ, CTCF, and other factors in disease processes. Currently, she holds a postdoctoral fellowship at the University of Miami Miller School of Medicine, where she is studying novel insulation factors on gene regulation during developmental and disease processes.

🔬 CONTRIBUTIONS AND RESEARCH FOCUS ON GENE REGULATION

Dr. Ortabozkoyun-Kara’s research has significantly advanced our understanding of epigenetics, stem cell biology, and cancer biology. Her work has centered on the intricate mechanisms of gene regulation, particularly the insulation functions that control the expression of Hox genes during development and in disease states. Through innovative CRISPR genetic screens and biochemical assays, she has identified key factors that cooperate with CTCF in these processes. Her research on the differences in Polycomb Repressive Complex composition during cellular differentiation has provided new insights into how these complexes contribute to the regulation of gene expression.

🌍 IMPACT AND INFLUENCE

Dr. Ortabozkoyun-Kara’s contributions to the fields of epigenetics and stem cell biology have had a profound impact on our understanding of how genetic and biochemical mechanisms lead to cellular diversity and disease. Her findings on the role of insulation factors in gene regulation have opened new avenues for research in developmental biology and cancer, influencing the direction of studies in these fields. Her expertise is recognized internationally, and she continues to collaborate with leading scientists to push the boundaries of what we know about gene regulation and its implications for human health.

📚 ACADEMIC CITATIONS

Dr. Ortabozkoyun-Kara’s work has been widely cited in the academic community, reflecting the importance of her contributions to the scientific understanding of gene regulation. Her publications in high-impact journals are frequently referenced by other researchers in the fields of molecular biology, genetics, and biochemistry. These citations underscore the relevance of her work to ongoing research and its potential to inform new therapeutic approaches for diseases linked to epigenetic regulation.

🏆 LEGACY AND FUTURE CONTRIBUTIONS

As Dr. Ortabozkoyun-Kara continues her research at the University of Miami, her legacy is one of innovation and discovery. Her future contributions are expected to further illuminate the complex mechanisms of gene regulation and their role in development and disease. With her deep expertise in epigenetics and stem cell biology, she is poised to make significant advances in the understanding and treatment of diseases driven by genetic and epigenetic alterations. Her work will undoubtedly continue to influence the fields of molecular biology and genetics for years to come, inspiring future generations of scientists.

💡 INNOVATIVE APPROACHES

Dr. Ortabozkoyun-Kara is known for her creative and methodical approaches to scientific research. She has developed novel genetic and biochemical methods that have expanded the toolkit available to researchers studying epigenetic mechanisms. Her work not only provides critical insights but also equips the scientific community with new strategies for investigating and manipulating gene expression in various biological contexts.

📑 NOTABLE PUBLICATIONS

"CRISPR and biochemical screens identify MAZ as a cofactor in CTCF-mediated insulation at Hox clusters" 

  • Authors: Havva Ortabozkoyun, Pin-Yao Huang, Hyunwoo Cho, Varun Narendra, Gary LeRoy, Edgar Gonzalez-Buendia, Jane A Skok, Aristotelis Tsirigos, Esteban O Mazzoni, Danny Reinberg
  • Journal: Nature Genetics
  • Year: 2022

"A CRISPR Screen Identifies Myc-associated Zinc Finger Protein (MAZ) as an Insulator Functioning at CTCF boundaries in Hox Clusters" 

  • Authors: Havva Ortabozkoyun-Kara, Pin-Yao Huang, Hyunwoo Cho, Varun Narendra, Gary Leroy, Jane A. Skok, Aristotelis Tsirigos, Esteban O. Mazzoni, Danny Reinberg
  • Journal: BioRxiv
  • Year: 2020

"Members of an array of zinc finger proteins specify distinct Hox chromatin boundaries"

  • Authors: Havva Ortabozkoyun, Pin-Yao Huang, Edgar Gonzalez-Buendia, Hyein Cho, Sang Kim, Aristotelis Tsirigos, Esteban Mazzoni, Danny Reinberg
  • Journal: bioRxiv
  • Year: 2023

"Members of a Family of Zinc Finger Proteins Demarcate Chromatin Boundaries at Hox Clusters during Development, Ortabozkoyun et. al"

  • Authors: Havva Ortabozkoyun, Pin-Yao Huang, Edgar Gonzalez-Buendia, Hyunwoo Cho, Sang Y Kim, Aristotelis Tsirigos, Esteban O Mazzoni, Danny Reinberg
  • Journal: Mendeley Data
  • Year: 2024

"Novel chromatin insulating activities uncovered upon eliminating known insulators in vivo"

  • Authors: Havva Ortabozkoyun, P. Huang, H. Cho, E. Mazzoni, A. Tsirigos, D. Reinberg
  • Year: 2023

Bruno Fuchs | Sarcoma | Excellence in Innovation

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Prof Dr. Bruno Fuchs | Sarcoma | Excellence in Innovation 

Swiss Sacroma Network | Switzerland 

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Bruno Fuchs, MD, PhD 🌟

Position: Professor and Chair, Sarcoma Center & Swiss Sarcoma Network

Location: Faculty of Health Science & Medicine, University of Lucerne, and LUKS University Hospital, Luzern, Switzerland

Contact: fuchs@sarcoma.surgery

Educational Background 🎓

  • 2022: Guest-Professor, Medical Faculty, University of Lucerne
  • 2010: Extraordinarius, Medical Faculty, University of Zurich
  • 2005: Associate Professor, Medical Faculty, University of Zurich
  • 2004: PhD in Biomedical Sciences (Tumor Biology), Mayo Graduate School, Mayo College of Medicine, Rochester, MN, USA
  • 1996 - 2004: Training and Fellowship in Orthopedic Surgery and Musculoskeletal Oncology at Mayo Clinic, Rochester, MN, USA, and Swiss institutions
  • 1992: MD, Medical Faculty, University of Zurich, Switzerland

Clinical and Research Expertise 🔬

  • Specializes in the surgical treatment of bone and soft tissue tumors in both pediatric and adult patients
  • Focuses on outcome analysis and quality indicators in sarcoma care
  • Engages in predictive outcome analytics for improving sarcoma treatment

Academic Contributions 📚

  • Authored over 200 publications and book chapters
  • Acquired over 10 million Swiss Francs in research funding
  • Active as a reviewer for prestigious journals and grant committees

Contributions and Research Focus on Sarcoma🏆

Fuchs has made profound contributions to the surgical treatment of bone and soft tissue tumors in both pediatric and adult patients. His research is heavily focused on the outcome analysis of sarcoma patients, defining and assessing quality indicators of sarcoma care, and predictive outcome analytics. His work is vital in improving the standards and methodologies employed in sarcoma care, directly impacting patient outcomes and care quality.

Public and Professional Service 🌐

  • Founder & Chair of the Swiss Sarcoma Network
  • Founder of the Sarcoma Academy
  • Member of multiple medical societies including SwissOrthopaedics, FMH, and CTOS

Dr. Bruno Fuchs is recognized internationally for his extensive contributions to the field of sarcoma research and treatment. His work continues to shape the future of musculoskeletal oncology.

Notable Publications📑

"Real-World-Time Data and RCT Synergy: Advancing Personalized Medicine and Sarcoma Care through Digital Innovation" 

  • Authors: Philip Heesen, Georg Schelling, Mirko Birbaumer, Ruben Jäger, Beata Bode, Gabriela Studer, Bruno Fuchs
  • Journal: Cancers
  • Year: 2024

"Improving Sarcoma Outcomes: Target Trial Emulation to Compare the Impact of Unplanned and Planned Resections on the Outcome" 

  • Authors: Timothy T. A. F. Obergfell, Kim N. Nydegger, Philip Heesen, Georg Schelling, Beata Bode-Lesniewska, Gabriela Studer, Bruno Fuchs
  • Journal: Cancers
  • Year: 2024

"Impact of Institutional Practices and Surgical Complexity on Sarcoma Surgery Costs: Driving Efficiency in Value-Based Healthcare"

  • Authors: Georg Schelling, Philip Heesen, Boris Malte Tautermann, Markus Wepf, Barbara Di Federico, Annika Frei, Kim van Oudenaarde, Pietro Giovanoli, Beata Bode-Lesniewska, Gabriela Studer et al.
  • Journal: Cancers
  • Year: 2024

"Development and Validation of the Bone Tumor Surgery Complexity Score"

  • Authors: Annika Frei, Georg Schelling, Philip Heesen, Pietro Giovanoli, Bruno Fuchs
  • Journal: Reports
  • Year: 2024

"Exploring Risk Factors for Predicting 30-Day Postoperative Morbidity in Musculoskeletal Tumor Surgery"

  • Authors: Philip Heesen, Maria Elyes, Jan Domanski, Georg Schelling, Sören Könneker, Bruno Fuchs
  • Journal: Journal of Clinical Medicine
  • Year: 2024

Ning Li | Gene Regulations | Best Researcher Award

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Dr. Ning Li | Gene Regulations | Best Researcher Award

Tianjin University | China

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Li Ning, Ph.D. 🧬

Lecturer, School of Disaster and Emergency Medicine, Faculty of Medicine

Research Areas :🧠

  • Molecular mechanisms of traumatic injury
  • Immunotherapy
  • Mechanobiology

📧 Email: lining620@tju.edu.cn

Brief Introduction:

Dr. Li Ning received her Ph.D. from Nankai University, China, in 2019. Since then, she has been a dedicated lecturer at Tianjin University, where she also supervises master's students. Her research delves into the pathogenic mechanisms of trauma, cell death in trauma-related diseases, immunotherapy, and biomechanics within disaster medicine. Dr. Ning has led numerous national, provincial, and university-level research projects, with her work published in esteemed journals like Nucleic Acids Research, Military Medical Research, Trends in Pharmacological Sciences, Cell Death & Discovery, and Pharmacological Research.

Educational Background 🎓

  • 2008.09 - 2012.07: Bachelor's in Bioscience and Biotechnology, Shenyang Agricultural University
  • 2012.09 - 2015.07: Master's in Medicine, Nankai University
  • 2015.09 - 2018.12: Ph.D. in Pharmacy, Nankai University

Professional Experience 💼

  • 2019.05 - Present: Lecturer, School of Disaster and Emergency Medicine, Faculty of Medicine, Tianjin University

Academic Achievements:

Dr. Li Ning has an impressive list of published research papers, several of which highlight her contributions to the understanding of cell death mechanisms and potential therapeutic targets for trauma management. Additionally, she holds multiple patents, including innovations in nucleic acid detection and crush injury modeling equipment.

Fellowships & Honors 🏆

  • Excellent Master's Thesis, Nankai University (2015)
  • Teaching and Educating Excellence Award, Tianjin University (2022)
  • Scientific Research Rookie Award, Tianjin University (2022)
  • Outstanding Mentor, Tianjin University (2023)
  • Multiple awards for outstanding contributions and excellence in teaching from Tianjin University (2022-2024)

Dr. Ning continues to contribute significantly to the fields of disaster and emergency medicine through her research and teaching.

Journal Publications 📚

  • Nucleic Acids Research
    • Li Ning might have contributed research on the molecular mechanisms of traumatic injury, possibly focusing on DNA damage and repair mechanisms or gene expression changes post-injury.
  • Military Medical Research
    • Research related to trauma, particularly in military settings, could include studies on immunotherapy and the impact of cell death on traumatic injuries, as well as advances in medical biomechanics.
  • Trends in Pharmacological Sciences
    • Likely publications could discuss cutting-edge approaches in immunotherapy or pharmacological interventions targeting trauma-induced pathogenesis.
  • Cell Death & Discovery
    • Studies on the role of cell death in trauma-related diseases, focusing on molecular pathways and therapeutic targets.
  • Pharmacological Research
    • Research papers could include findings on drug interventions for trauma-induced pathologies, including immunotherapeutic strategies and their mechanobiological implications.

Notable Publications 📑

"Ferroptosis in acute kidney injury following crush syndrome: A novel target for treatment" 

  • Authors: Qiao, O., Wang, X., Wang, Y., Li, N., Gong, Y.
  • Journal: Journal of Advanced Research
  • Year: 2023

"Biotherapy of experimental acute kidney injury: emerging novel therapeutic strategies" 

  • Authors: Li, N., Han, L., Wang, X., Zhang, L., Gong, Y.
  • Journal: Translational Research
  • Year: 2023

"Delayed step-by-step decompression with DSF alleviates skeletal muscle crush injury by inhibiting NLRP3/CASP-1/GSDMD pathway "

  • Authors: Li, N., Wang, X., Wang, Y., Fan, H., Gong, Y.
  • Journal: Cell Death Discovery
  • Year: 2023

"Low GPR81 in ER+ breast cancer cells drives tamoxifen resistance through inducing PPARα-mediated fatty acid oxidation"

  • Authors: Yu, J., Du, Y., Liu, C., Wang, Y., Qin, J.
  • Journal: Life Sciences
  • Year: 2024

"Low GPR81 in ER+ breast cancer cells drives tamoxifen resistance through inducing PPARα-mediated fatty acid oxidation"

  • Authors: Xie, Y., Shan, M., Yu, J., Lan, L., Wang, Y.
  • Journal: Cancer Science
  • Year: 2024

Li Wan | Bipolar Disorder | Best Researcher Award

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Prof Li Wan | Bipolar Disorder | Best Researcher Award

Affiliated Psychological Hospital Of Anhui Medical University | China

Author Profile 

Scopus

Orcid ID

Dr. Li Wan: Expert in Cognitive Neuropsychology and Neuromodulation 🧠

Educational Background 🎓

  • Ph.D. in Psychology (2006) - Virginia Polytechnic Institute and State University, Virginia, USA
  • Master of Psychology (2004) - Virginia Polytechnic Institute and State University, Virginia, USA
  • Bachelor of Clinical Medicine (1998) - Hubei University of Medicine, Hubei, China

Professional Experience 💼

  • Adjunct Professor (2022-present) - Anhui Medical University, Hefei, China
  • Director (2021-present) - Brain Disorders and Neuromodulation Research Center, Anhui Mental Health Center, Hefei, China
  • Co-Principal Investigator (2018-2021) - Cognitive Neuropsychology Lab, University of Science and Technology of China, Hefei, China
  • Research Scientist (2014-2018) - School of Medicine, University of Missouri-Kansas City; Center for Behavioral Medicine/Department of Mental Health, Missouri, USA
  • Clinical Assistant Professor/Post-doc Fellow (2007-2013) - Department of Psychiatry and Behavioral Science, Texas A&M University and Central Texas Veterans Health Care System; Department of Psychology and Neuroscience, Baylor University, Texas, USA
  • Teaching/Research Assistant (2002-2006) - Department of Psychology, Virginia Tech, Virginia, USA

Fellowships & Honors 🏆

  • Anhui Province ‘Overseas High-level Talents’ Award (2019)
  • Fellowship, Athinoula A. Martinos Center for Biomedical Imaging, Harvard University (2010)
  • Travel Award, Graduate Student Association, Virginia Tech (2006)
  • Galper Fund Award, Department of Psychology, Virginia Tech (2005)
  • Multiple Travel Awards (2004-2006) - 1st, 2nd, and 3rd Joint ECNS and ISNIP Conferences
  • Graduate Research Development Project Grant, Virginia Tech (2003)

Affiliations & Memberships 🌐

  • Deputy Secretary - Sleep Branch, China Traditional Chinese Medicine Information Conference
  • Vice Director - Cognitive Behavioral Therapy Committee, Anhui Psychological Health Association
  • Member - World Psychiatric Association (WPA), Society for Psychophysiological Research (SPR), Cognitive Neuroscience Society (CNS)
  • Editorial Board Member - Brain Science Advances, Journal of Brain Research and Neurology, World Journal of Clinical Medicine Research, International Journal of Psychological and Brain Sciences, Advances in Health and Behavior
  • Reviewer - NeuroImage, Human Brain Mapping, Neural Regeneration Research, Psychophysiology, International Journal of Psychophysiology, Journal of Psychiatry Research, Psychiatry Research, and more

Journal Publications 📚

Dr. Li Wan has contributed significantly to the fields of psychology and neuroscience, with numerous publications in prestigious journals such as Heliyon, Human Brain Mapping, Frontiers in Psychology, Laboratory Medicine, and World Psychiatry. Her research covers a broad spectrum of topics, including affective disorders, brain morphology, cognitive neuropsychology, and the neural mechanisms underlying behavioral and psychiatric conditions.

Notable Publications 📑

"The neural mechanisms of immediate and follow-up of the treatment effect of hypnosis on smoking craving" 

  • Authors: Li, X., Chen, L., Ma, R., Rao, H., Zhang, X.
  • Journal: Brain Imaging and Behaviour
  • Year: 2020

"The Effect of Vocabulary Depth and Breadth on English Listening Comprehension Can Depend on How Comprehension Is Measured " 

  • Authors: Luo, Y., Song, H., Wan, L., Zhang, X.
  • Journal: Frontiers in Psychology
  • Year: 2021

"Laboratory Predictors of COVID-19 Pneumonia in Patients with Mild to Moderate Symptoms "

  • Authors: Li, J., Wan, L., Feng, Y., Zhang, X., Xia, M
  • Journal: Lab Medicine
  • Year: 2021

"Brain morphology, harm avoidance, and the severity of excessive internet use"

  • Authors: Wan, L., Zha, R., Ren, J., Zuo, H., Zhang, X.
  • Journal: Human Brain Mapping
  • Year: 2022

"Decision tree distinguish affective disorder diagnosis from psychotic disorder diagnosis with clinical and lab factor"

  • Authors: Liu, X., Wang, X., Wen, C., Wan, L.
  • Journal: Heliyon
  • Year: 2022

Ali Mahmoud Ali Ahmed | Neurogenetics | Best Researcher Award

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Dr. Ali Mahmoud Ali Ahmed | Neurogenetics | Best Researcher Award

The Royal Wolverhampton NHS Trust | United Kingdom

Author Profile

Scopus

Orcid ID

Google Scholar

Biography of Ali Mahmoud Ali Ahmed 🌟

Current Positions

  • Senior Clinical Fellow of Neurology (Jan 2024 - Present)
  • Neurology Specialist (MD Registrar) (June 2022 - Present)
    • Faculty of Medicine, Al-Azhar University 🌐
    • Al-Azhar University
    • Supervisor: Prof. Emad Fawzy, MD

Previous Positions

  • Neurology Specialist (Jan 2022 - Jan 2024)
  • Neurology Resident (MSc Registrar) (June 2019 - 2021)
    • Faculty of Medicine, Al-Azhar University
    • Supervisor: Prof. Mohamed Al-Bahay MG Reda, MD
  • House Officer (March 2018 - February 2019)
    • Al-Azhar University Hospitals

Clinical Experience 🩺

  • Neuro-genetics: Diagnosis and management of neurogenetic disorders.
  • Neuro-intensive care: Stroke unit management with extensive experience in critical cases.
  • Neuro-intervention: Performing diagnostic angiography and assisting in therapeutic procedures.
  • Neuroimmunology: Management of autoimmune CNS disorders.
  • Neurophysiology: Expertise in nerve conduction studies, EMG, and EEG.
  • Neuro-pediatrics: Management of neurological disorders in children.
  • Epilepsy: Treatment and management of epilepsy in adults and children.
  • Movement Disorders: Management of abnormal movements, including botulinum toxin injection.
  • Headaches: Treatment of various headache types.

Education 🎓

  • Medical Doctorate in Clinical Neurology (MD) (June 2022 - Present)
    • Faculty of Medicine, Al-Azhar University
  • Master of Clinical Neuro-Psychiatry (MSc) (June 2019 - 2022)
    • Faculty of Medicine, Al-Azhar University
  • Bachelor of Medicine and Bachelor of Surgery (MBBCh) (Oct 2011 - Dec 2017)
    • Faculty of Medicine, Al-Azhar University
    • Graduated among the top 10% with a GPA of 3.84

Honors, Awards, and Grants 🏅

  • 2017 IBRO-ISN School on Neurogenetics
  • 2nd Best Presentation on Mesenchymal Stem Cells (2014)
  • Award of Excellence in Histology (2013)
  • Al-Azhar Scholarship for Top Ten Students in the Republic (2011)

Language Skills 🌐

  • English
  • Arabic

Reviewer for Journals 📝

  • Medical Science Monitor
  • BMC Infectious Diseases
  • Tropical Medicine and Health (TMAH)
  • PLOS ONE

Research Instructor at Online Research Club 🧪

  • Primary projects on novel anti-hemozoin drugs and HBV gene mutations.
  • Conducted clinical trials and epidemiological studies.
  • Developed research methodologies and meta-analyses.

Teaching Experience 📚

  • Conducted numerous lectures and workshops on meta-analysis, medical statistics, and research methodologies.
  • Chief instructor for various research courses and diplomas.

Notable Publications

Prevalence and burden of dengue infection in Europe: A systematic review and meta-analysis

  • Authors: Ahmed, A.M., Mohammed, A.T., Vu, T.T., ... Hirayama, K., Huy, N.T.
  • Journal: Reviews in Medical Virology
  • Year: 2020

Association of Allergic Symptoms with Dengue Infection and Severity: A Systematic Review and Meta-analysis

  • Authors: Kien, N.D., El-Qushayri, A.E., Ahmed, A.M., ... Hirayama, K., Huy, N.T.
  • Journal: Virologica Sinica
  • Year: 2020

Erratum: Correction to: Association of Allergic Symptoms with Dengue Infection and Severity: A Systematic Review and Meta-analysis

  • Authors: Kien, N.D., El-Qushayri, A.E., Ahmed, A.M., ... Hirayama, K., Huy, N.T.
  • Journal: Virologica Sinica
  • Year: 2020

Factors associated with the success of trial without catheter in acute urinary retention due to benign prostatic hyperplasia

  • Authors: Phuong Hoai, D., Thang Tai, L., Huu Loc, T., ... Huy, N., Khanh, L.
  • Journal: Urological Science
  • Year: 2021

Outcomes of pregnancy in Egyptian women with multiple sclerosis in the new treatment era: a multi-center retrospective observational study

  • Authors: Ahmed, A.M., Reda, M.A.-B.M.G., Elsheshiny, A.H.
  • Journal: Egyptian Journal of Neurology, Psychiatry and Neurosurgery
  • Year: 2021

Aline Cesar | Nutrigenomics | Excellence in Research

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Assoc Prof Dr. Aline Cesar | Nutrigenomics | Excellence in Research

Esalq (Luiz De Queiroz College of Agriculture) | Brazil

Aline Silva Mello Cesar 🌟

Early Academic Pursuits 📚

Aline Silva Mello Cesar embarked on her academic journey with a strong foundation in animal science. She obtained her Bachelor's degree in Animal Science from the University of São Paulo in 2007. Her passion for veterinary science led her to pursue a Master's degree at the Federal University of Uberlândia, where she graduated in 2010. Aline continued her academic excellence by earning a Doctorate in Animal Science and Pastures from the University of São Paulo in 2014.

Professional Endeavors 💼

Aline's professional career is marked by a series of significant roles and contributions:

  • February 2023 - Present: President of the Research and Innovation Committee at ESALQ, University of São Paulo
  • December 2019 - Present: Associate Professor at the University of São Paulo
  • February 2020 - Present: Vice-coordinator at the Centre for Functional Genomics – ESALQ/USP
  • March 2020 - Present: Researcher with a fellowship at CNPq
  • 2014 - 2017: Post-Doctoral Researcher at ESALQ, University of São Paulo
  • 2015 - 2016: Visiting Scholar at Iowa State University, USA
  • 2012 - 2013: Visiting Scholar at Iowa State University, USA
  • Feb. 2007 - April 2007: Visiting Scholar at Parco Tecnologico Padano, Italy

Contributions and Research Focus 🔬

Aline Silva Mello Cesar has made notable contributions in the field of animal science, particularly in genetics and functional genomics. Her research focuses on:

  • Genetics and Animal Improvement
  • Bioinformatics and Computational Biology
  • Functional Genomics

Her work has had a significant impact on understanding the genetic basis of animal traits, improving breeding programs, and advancing the field of bioinformatics.

Impact and Influence 🌍

Aline has been recognized with several awards and honors, reflecting her influence and impact in her field:

  • 2023: Young Bioinformatician Award - Best Dissertation, X-Metting 2023
  • 2023: Honorable Mention of the Horácio Schneider Award in Genetics and Animal Improvement
  • 2022: Honorable Mention at the 30th SIICUSP
  • 2021: Scientific Merit Award, Brazilian Society for Animal Genetic Improvement
  • 2020: Best video about COVID-19 efforts, University of São Paulo
  • 2018: Travel Fellowship Award, RNA Society Meeting 2018, Berkeley, CA, USA
  • 2016: Travel Fellowship Award, PAG Conference 2016, San Diego, CA
  • 2011: Olympiad of Innovation, University of São Paulo
  • 2005: Honor mention, 13th Siicusp, University of São Paulo

Academic Cites 📜

Aline's research and expertise are well-regarded in various scientific journals. She has contributed to and reviewed for numerous publications, including:

  • 2010 - Present: Molecular Biology Reports
  • 2015 - Present: PLOS ONE
  • 2016 - Present: Livestock
  • 2017 - Present: Scientia Agricola
  • 2018 - Present: Scientific Reports
  • 2018 - Present: BMC Genomics
  • 2019 - Present: Animal Genetics
  • 2020 - Present: Frontiers in Genetics (Editor)
  • 2020 - Present: Animals

Legacy and Future Contributions 🌟

Aline Silva Mello Cesar’s dedication to her field has left a lasting legacy. Her pioneering work in genetics and bioinformatics continues to inspire new research and innovation. As she progresses in her career, Aline is poised to make even more significant contributions to the scientific community, shaping the future of animal science and genetics.

Notable Publications 📑

"Bivariate GWAS Reveals Pleiotropic Regions among Feed Efficiency and Beef Quality-Related Traits in Nelore Cattle" 📊

  • Authors: Buss, C.E., Afonso, J., de Oliveira, P.S.N., Mourão, G.B., de Almeida Regitano, L.C.
  • Journal: Mammalian Genome
  • Year: 2023

"Brain Fatty Acid and Transcriptome Profiles of Pig Fed Diets with Different Levels of Soybean Oil" 🧠

  • Authors: da Silva, B.P.M., Fanalli, S.L., Gomes, J.D., Luchiari Filho, A., Cesar, A.S.M.
  • Journal: BMC Genomics
  • Year: 2023

"Transcriptome Profile of Skeletal Muscle Using Different Sources of Dietary Fatty Acids in Male Pigs" 💪

  • Authors: Fanalli, S.L., da Silva, B.P.M., Gomes, J.D., Luchiari Filho, A., Cesar, A.S.M.
  • Journal: Functional and Integrative Genomics
  • Year: 2023

"Novel Putative Causal Mutations Associated with Fat Traits in Nellore Cattle Uncovered by eQTLs Located in Open Chromatin Regions" 🧬

  • Authors: Garcia, I.S., Silva-Vignato, B., Cesar, A.S.M., Mourão, G.B., Coutinho, L.L.
  • Journal: Scientific Reports
  • Year: 2024

"Phenotypic Divergence between Broiler and Layer Chicken Lines is Regulated at the Molecular Level during Development" 🐔

  • Authors: Contriciani, R.E., Grade, C.V.C., Buzzatto-Leite, I., Coutinho, L.L., Alvares, L.E.
  • Journal: BMC Genomics
  • Year: 2024