SUNY Downstate Health Sciences University | United States
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YANI ARHAB, PHD 🎓🔬
EARLY ACADEMIC PURSUITS 📚
Yani Arhab’s academic journey began at the University François Rabelais of Tours (France), where he earned his BSc in Biology. During his studies, he participated in an Erasmus program, studying at Queen Mary University of London. He continued his education at University Claude Bernard Lyon1, completing his Master's in Structural & Functional Biochemistry. Yani further honed his skills during a Master’s 2 training at the ICBMS, where he worked on the structural and functional characterization of phospholipases D in plants.
PROFESSIONAL ENDEAVORS 💼
Yani's career spans multiple prestigious institutions and roles. From 2015 to 2018, he earned his PhD at the University of Lyon, where he focused on phospholipases D, under the guidance of Pr. A. Abousalham and Dr. A. Noiriel. Following this, he served as a full-time associate professor at Université Claude Bernard Lyon1 in 2018-2019. Since 2019, Yani has been a Postdoctoral Associate at the State University of New York, Downstate Medical Center, where he is studying the reconstitution of ribosomal initiation complexes on viral RNA Internal Ribosome Entry Sites (IRES) under the mentorship of Dr. Christopher Hellen and Dr. Tatyana Pestova.
CONTRIBUTIONS AND RESEARCH FOCUS ON VIRAL STRATEGIES🧬
Yani’s research focuses on biochemistry, particularly in the areas of ribosomal initiation, lipid biochemistry, and the structural and functional analysis of enzymes. His work on phospholipases D has contributed significantly to understanding lipid metabolism and its impact on cellular functions. In his current research, he is studying viral RNA IRES and their mechanisms in translation initiation, which has important implications for viral infections and potential therapeutic targets.
IMPACT AND INFLUENCE 🌍
Yani’s work is influencing multiple fields of molecular biology and biochemistry, particularly through his contributions to understanding the molecular mechanisms behind viral translation and enzyme function. His research on IRES mechanisms is helping expand our knowledge of viral RNA translation, with the potential to influence future antiviral strategies.
ACADEMIC CITATIONS 📈
Throughout his academic career, Yani Arhab has gained recognition for his innovative research, presenting his findings at international conferences such as the Translational Control Symposium at Cold Spring Harbor Laboratory and the Ribosome Structure & Function Conference. His research contributions have resulted in numerous publications and are frequently cited by peers in the fields of biochemistry, molecular biology, and virology.
LEGACY AND FUTURE CONTRIBUTIONS 🔮
Yani Arhab’s legacy is defined by his commitment to advancing our understanding of molecular biology. He has built a solid foundation of research that will continue to shape the future of biochemical research, particularly in the fields of RNA biology and viral research. Looking ahead, he plans to further investigate the complex interactions of ribosomal initiation and their implications for therapeutic development, particularly for viral diseases.
AWARDS AND SCHOLARSHIPS 🏆
- 2015, 2016, 2018: Research funds from the Ligue National Contre le Cancer (€15,000)
- 2017: FEBS+3 travel grant (€750)
- 2015: Ph.D. bursary recipient
PROFESSIONAL MEMBERSHIPS 🤝
- Member of the AFC (French Crystallography Society)
- Member of the SFBBM (French Molecular Biology and Biochemistry Society)
- Associate Professor in Biochemistry and Molecular Biology since 2019
TEACHING EXPERIENCE 🍎
Yani Arhab has contributed to the education of future scientists by teaching both lectures and experimental courses in biochemistry. He has mentored undergraduate students in subjects such as protein purification, lipid characterization, and enzymatic assays, fostering the next generation of researchers. Yani Arhab's work exemplifies the intersection of molecular research and practical application in medicine, showcasing his contributions to both academia and the scientific community at large.
NOTABLE PUBLICATIONS 📑
"Heterologous expression, kinetic characterization and molecular modeling of a new sn-1,3-regioselective triacylglycerol lipase from Serratia sp. W3"
- Authors: Eddehech, A. , Rahier, R. , Smichi, N. , Sayari, A. , Zarai, Z.
- Journal: Process Biochemistry
- Year: 2021
"Phospholipase D inhibitors screening: Probing and evaluation of ancient and novel molecules"
- Authors: Arhab, Y. , Bessaa, K. , Abla, H. , Abousalham, A. , Noiriel, A
- Journal: International Journal of Biological Macromolecules
- Year: 2021
"Corrigendum to “Production, purification and functional characterization of phospholipase C from Bacillus thuringiensis with high catalytic activity”
- Authors: Eddehech, A. , Smichi, N. , Arhab, Y. , Gargouri, Y. , Zarai, Z.
- Journal: Process Biochemistry
- Year: 2019
"Production, purification and functional characterization of phospholipase C from Bacillus thuringiensis with high catalytic activity"
- Authors: Eddehech, A. , Smichi, N. , Arhab, Y. , Gargouri, Y. , Zarai, Z.
- Journal: Process Biochemistry
- Year: 2019
"Plant phospholipase D mining unravels new conserved residues important for catalytic activity"
- Authors: Arhab, Y. , Abousalham, A. , Noiriel, A.
- Journal: Molecular and Cell Biology of Lipids
- Year: 2019