Jiangsu University | China
Author Profile
Scopus
Dr. Shi Haifeng: Pioneer in Metal Toxicology and Cell Damage Detection 🔬
EARLY ACADEMIC PURSUITS 🎓
Dr. Shi Haifeng's academic journey began with a Bachelor’s degree in Biochemistry from Nanjing University in 1998. His passion for biochemistry led him to pursue a Ph.D. at the Hong Kong University of Science and Technology, where he studied under the mentorship of Professor Hong Xue, earning his doctorate in 2002. This foundation set the stage for his future groundbreaking research in the field of metal ion metabolism and toxicity.
PROFESSIONAL ENDEAVORS 🧑🔬
After obtaining his Ph.D., Dr. Shi continued his work at the Hong Kong University of Science and Technology as a Research Associate from 2002 to 2004, further honing his research skills. He then embarked on an international academic experience as a Visiting Scholar at the National Institutes of Health (NIH), specifically within the Liver Diseases Branch of the NIDDK, from 2004 to 2009. His time at the NIH allowed him to deepen his expertise in molecular toxicology and disease mechanisms.
Dr. Shi’s research is focused on the metabolism and biological toxicity of metal ions such as iron, copper, and cadmium. His work is crucial in understanding how these metals impact biological systems, particularly in the context of heavy metal nephropathy. Additionally, his innovative work on the use of cell-free circulating cfDNA in blood as a biomarker for tissue cell damage has broad applications in medical diagnostics and environmental toxicology. His experimental models, which include yeast, silkworms, and mice, have helped to clarify the toxicological effects of metals at both molecular and systemic levels.
IMPACT AND INFLUENCE 🌍
Dr. Shi’s contributions to the scientific community are widely recognized. He has published over 70 research papers in prestigious international journals. One of his papers was recommended by Professor Alan Parrish from the University of Missouri-Columbia and listed by "Faculty Opinions" (formerly F1000Prime), a distinction reserved for papers with significant impact on their field. Another of his publications has been selected as an ESI Highly Cited Paper, placing him among the top 1% of researchers in his field.
ACADEMIC CITATIONS 📚
Dr. Shi’s work is highly cited, and his recognition as an ESI Highly Cited Researcher underscores his influence on the global scientific community. His papers continue to guide researchers in the fields of toxicology, nephropathy, and medical diagnostics.
LEGACY AND FUTURE CONTRIBUTIONS 🏅
Dr. Shi Haifeng’s legacy lies in his groundbreaking work on the biological effects of heavy metals and his innovative use of cfDNA in disease detection. As a leader in his field, his future contributions are expected to expand the frontiers of biochemistry and toxicology, with significant implications for both environmental health and clinical medicine. His continued dedication to both research and education ensures that he will remain an influential figure in his field for years to come.
NOTABLE PUBLICATIONS 📑
"Cadmium promoted LPS-induced inflammation through TLR4/IκBα/NFκ-B signaling by increasing ROS-mediated incomplete autophagy"
- Authors: Guo, C. , Ruan, J. , Li, Z. , Gu, J. , Shi, H.
- Journal: Ecotoxicology and Environmental Safety
- Year: 2024
"From ferroptosis to cuproptosis, and calcicoptosis, to find more novel metals-mediated distinct form of regulated cell death"
- Authors: Gu, J. , Guo, C. , Ruan, J. , Gong, X. , Shi, H.
- Journal: Apoptosis
- Year: 2024
"Stimuli-triggered multilayer films in response to temperature and ionic strength changes for controlled favipiravir drug release"
- Authors: Xu, L. , He, L. , Li, Y. , Shi, H. , Zhu, C.
- Journal: Biomedical Materials (Bristol)
- Year: 2024
"Energy storage enabled by cross-linked multilayer films using block copolymer-modified nanocapsules and chitosan biopolymers"
- Authors: Xu, L. , Li, Y. , Cai, T. , Chu, Z. , Shen, X
- Journal: Macromolecular Research
- Year: 2024
"Analysis of the primary factors influencing donor derived cell-free DNA testing in kidney transplantation"
- Authors: Cao, C. , Yuan, L. , Wang, Y. , Shi, H. , Jiang, T.
- Journal: Frontiers in Immunology
- Year: 2024