Huazhong University of Science and Technology | China
Author Profile
Scopus
👨⚕️ BIOGRAPHY OF CHAOHUA DENG
🏛 EARLY ACADEMIC PURSUITS
Chaohua Deng was born on April 12, 1988. He embarked on his academic journey in clinical medicine at Wuhan University, where he earned his Bachelor's degree in Clinical Medicine in 2011. Demonstrating a keen interest in advancing his expertise, he pursued a Master’s degree in Clinical Medicine at Wuhan University, completing it in 2013. Seeking further specialization, he continued his studies abroad and obtained a Ph.D. in Life and Health Sciences from the University of Lorraine, France, in 2017. His doctoral research contributed significantly to his understanding of ophthalmology and related biomedical sciences.
👨⚕️ PROFESSIONAL ENDEAVORS
Deng’s professional career has been dedicated to clinical ophthalmology, with progressive advancements in his roles at Tongji Hospital, Huazhong University of Science and Technology:
- Physician (2017-2019): Started as a physician in the Department of Ophthalmology, where he gained hands-on experience in diagnosing and treating ophthalmic conditions.
- Attending Physician (2019-Present): Promoted to Attending Physician, Deng played a more active role in patient care, surgical interventions, and medical research.
- Associate Chief Physician (2022-Present): Achieved a senior position where he leads research projects and continues to contribute to clinical advancements in ophthalmology.
🏥 CONTRIBUTIONS AND RESEARCH FOCUS ON OSTEOARTHRITIS
Deng's research primarily focuses on the molecular mechanisms underlying eye diseases and innovative treatment approaches. His National Natural Science Foundation of China (NSFC) projects reflect his commitment to advancing ophthalmic science:
- Irisin Activation in Trabecular Cells (Ongoing, Participant, 2023-2026): Investigating the Integrin αVβ5-Rac1 signaling pathway in trabecular meshwork cells to enhance aqueous outflow, a crucial area for glaucoma treatment.
- Vitamin K and Trabecular Meshwork Aqueous Outflow (Completed, Principal Investigator, 2022-2024): Explored how Vitamin K upregulates MGP expression in trabecular cells, which can improve fluid dynamics in the eye.
- Single-Cell Transcriptome Analysis on Retinal Injury (Completed, Participant, 2021-2024): Studied the role of Sideroflexin3 in retinal recovery through single-cell transcriptomics.
🌍 IMPACT AND INFLUENCE
Deng has made valuable contributions to the ophthalmology community through his clinical expertise and research. His findings have potential implications for glaucoma treatment, retinal injury recovery, and overall eye health. His involvement in international academic conferences has allowed him to share insights and collaborate with global experts.
📚 ACADEMIC CITES AND AWARDS
- Patent Contribution (2018): Co-author of a patent on mineralocorticoid receptor antagonists for osteoarthritis treatment (WIPO PCT/EP2017/068785).
- International Conference Participation (2016-2017): Attended the OARSI World Congress on Osteoarthritis in Amsterdam, Netherlands, presenting his work to an esteemed audience of researchers.
🏆 LEGACY AND FUTURE CONTRIBUTIONS
Chaohua Deng’s legacy is built upon his clinical excellence, research innovations, and contributions to ophthalmology. As an Associate Chief Physician, he is well-positioned to mentor young professionals, drive future research in ocular disease mechanisms, and pioneer new treatment modalities for eye conditions. His work continues to influence the field, with ongoing research that aims to enhance vision care and therapeutic strategies for ophthalmic diseases.
📑 NOTABLE PUBLICATIONS
"Irisin attenuates acute glaucoma-induced neuroinflammation by activating microglia-integrin αVβ5/AMPK and promoting autophagy "
- Authors: Q., Zhang, Qiuxiang , S., Xiang, Sifei , X., Chen, Xi , C., Deng, Chaohua , J., Wang, Junming
- Journal: International Immunopharmacology
- Year: 2024
"Beneficial Impact of Eicosapentaenoic Acid on the Adverse Effects Induced by Palmitate and Hyperglycemia on Healthy Rat Chondrocyte "
- Authors: C., Deng, Chaohua , N., Presle, Nathalie , A., Pizard, Anne , A., Bianchi, Arnaud , H., Kempf, Hervé
- Journal: International Journal of Molecular Sciences
- Year: 2024