Liang Liu | Molecular Neuroscience | Best Researcher Award

Prof. Dr. Liang Liu | Molecular Neuroscience | Best Researcher Award

Xiamen University | China

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🌟 Biography of Dr. Liang Liu 🌟

🎓 EARLY ACADEMIC PURSUITS

Dr. Liang Liu began his journey in the field of life sciences with a Bachelor of Science degree from the School of Life Sciences, South-Central University for Nationalities (2006–2010). His academic curiosity led him to pursue a Ph.D. at the School of Biology and Biological Engineering, South China University of Technology, where he delved into the intricate world of molecular biology (2010–2015).

🏛️ PROFESSIONAL ENDEAVORS

After earning his Ph.D., Dr. Liu undertook postdoctoral research at the prestigious Institute of Biophysics, Chinese Academy of Sciences (2015–2019). Since 2019, he has been a professor at the School of Life Sciences, Xiamen University. He also holds roles as a professor at the State Key Laboratory of Cell Stress Biology and Xiang’an Hospital Affiliated to Xiamen University.

Dr. Liu's leadership and expertise are further amplified through his contributions as a doctoral supervisor, shaping the next generation of researchers in molecular biology and gene editing.

🔬 CONTRIBUTIONS AND RESEARCH FOCUS ON MOLECULAR NEUROSCIENCE

Dr. Liang Liu’s research portfolio spans cutting-edge domains:

  1. Gene Editing and Diagnostic Tools: Developing and applying innovative tools for gene editing and molecular diagnostics.
  2. Prokaryotic Defense and Viral Antagonism: Exploring molecular mechanisms of prokaryotic defense systems, including CRISPR-Cas systems, and viral strategies for evading host immunity.
  3. Nucleic Acid Processing: Investigating RNA processing, regulation, and nucleic acid methylation modifications.
  4. Structural Biology of RNA: Elucidating RNA-mediated gene expression and regulation through advanced structural biology techniques.

His groundbreaking research has unveiled mechanisms underlying prokaryotic resistance to viruses and contributed to the development of novel gene-editing tools and efficient molecular diagnostic systems.

🏆 HONORS AND AWARDS

Dr. Liu’s exemplary contributions have earned him multiple prestigious honors, including:

  • Outstanding Youth Science Foundation Award (2020).
  • Young Top Talents Program, Xiamen University (2019).
  • Young Talents Support Project, China Association for Science and Technology (2018).
  • Second Prize, Beijing Science and Technology Award (2018).

🌍 IMPACT AND INFLUENCE

Dr. Liu has significantly advanced the understanding of prokaryotic defense systems, especially the CRISPR-Cas system. His insights into Cas nuclease mechanisms have laid the foundation for transformative molecular diagnostic tools. He has also pioneered innovative gene-editing tools, expanding the potential for therapeutic applications.

Through his role as a researcher and educator, he has mentored numerous students, fostering talent in molecular biology and structural biology.

đź“š ACADEMIC CITATIONS

Dr. Liu’s research is widely recognized in the scientific community. He has published extensively as a corresponding, co-corresponding, or first author in leading journals such as:

  • Cell
  • Nature Biotechnology
  • Molecular Cell
  • Nature Communications
  • eLife
  • Structure

His contributions have attracted numerous citations, reflecting his research's profound influence and relevance.

🌟 LEGACY AND FUTURE CONTRIBUTIONS

Dr. Liu’s legacy in molecular biology lies in his impactful work on the mechanisms of prokaryotic defense, innovative diagnostic tools, and advancements in RNA-based research. Moving forward, he is poised to drive significant breakthroughs in epigenetic inheritance, nucleic acid manipulation, and biomedical applications of gene-editing technologies. His continued efforts will undoubtedly contribute to shaping the future of molecular diagnostics and therapeutics.

📑 NOTABLE PUBLICATIONS 

"Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States" 

  • Authors: Sun, W. , Yang, J. , Cheng, Z. , Sontheimer, E.J. , Wang, Y.
  • Journal: Molecular Cell
  • Year: 2019

"Phage AcrIIA2 DNA Mimicry: Structural Basis of the CRISPR and Anti-CRISPR Arms Race" 

  • Authors: Liu, L. , Yin, M. , Wang, M. , Wang, Y.
  • Journal: Molecular Cell
  • Year: 2019

"Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference" 

  • Authors: You, L. , Ma, J. , Wang, J. , Zhang, X. , Wang, Y.
  • Journal: Cell
  • Year: 2019

"A CRISPR-Cas13a system for efficient and specific therapeutic targeting of mutant KRAS for pancreatic cancer treatment" 

  • Authors: Zhao, X. , Liu, L. , Lang, J. , Wang, Y. , Nie, G.
  • Journal: Cancer Letters
  • Year: 2018

"The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a" 

  • Authors: Liu, L. , Li, X. , Ma, J. , Zhang, X. , Wang, Y.
  • Journal: Cell
  • Year: 2017

Richard Lu | Neurodegenerative Diseases | Best Researcher Award

Prof Richard Lu | Neurodegenerative Diseases | Best Researcher Award

Cincinnati Children's Hospital Medical Center | United States

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Early Academic Pursuits

Qing Richard Lu embarked on his academic journey with a Bachelor of Science in Biochemistry from Peking Normal University in Beijing, China, which he completed in 1988. Following this, he pursued a Master of Science in Biophysics at Rutgers University, New Jersey, USA, completing his degree in 1993. He continued his studies at Rutgers University, earning a Ph.D. in Biochemistry in 1997 under the mentorship of Dr. Masayori Inouye.

Professional Endeavors

Dr. Lu's professional career began with a postdoctoral fellowship at the Dana-Farber Cancer Institute, Harvard Medical School, from 1997 to 2002. He worked with Dr. Chuck D. Stiles and collaborated with Dr. David Rowitch. In 2002, he joined the UT Southwestern Medical Center as an Assistant Professor in the Department of Developmental Biology, where he held the position of Southwestern Medical Foundation Endowed Scholar in Medical Research. He was promoted to Associate Professor with tenure in 2009 and continued in this role until 2013. In 2013, Dr. Lu joined Cincinnati Children’s Hospital Medical Center and the University of Cincinnati College of Medicine. He currently holds the position of Professor with tenure in the Department of Pediatrics. Additionally, he serves as the Scientific Director of the Brain Tumor Center and Program Leader of the Brain Tumor Program in the Division of Experimental Hematology and Cancer Biology, Cancer & Blood Diseases Institute.

Contributions and Research Focus on Neurodegenerative Diseases

Dr. Lu's research primarily focuses on the molecular and cellular mechanisms underlying brain tumors. His work is significant in understanding the biology of brain cancer and developing new therapeutic strategies. He has made notable contributions to the field of experimental hematology and cancer biology through his research on brain tumor development, progression, and treatment.

Impact and Influence

Throughout his career, Dr. Lu has influenced the field of pediatric oncology and neurobiology. His research has provided insights into the genetic and biochemical pathways involved in brain tumors, contributing to the development of novel therapeutic approaches. His work has been recognized through various academic appointments and endowed scholarships, reflecting his significant impact on medical research.

Academic Cites

Dr. Lu's work has been widely published in numerous scientific journals, and his research findings are frequently cited by peers in the field. His publications contribute to the broader scientific understanding of brain tumors and their treatment, solidifying his reputation as a leading expert in the field.

Legacy and Future Contributions

As a leading figure in pediatric oncology and neurobiology, Dr. Lu's legacy is marked by his commitment to advancing scientific knowledge and improving patient outcomes. His ongoing research efforts and leadership roles at Cincinnati Children’s Hospital Medical Center and the University of Cincinnati College of Medicine continue to shape the future of brain tumor research and treatment. Dr. Lu’s future contributions are expected to further enhance the understanding and management of brain tumors, paving the way for innovative therapeutic solutions and improved patient care.

Notable PublicationsÂ