Jinri Chen | Biosensor | Best Researcher Award

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Assist. Prof. Dr. Jinri Chen | Biosensor | Best Researcher Award

Jiangsu Ocean University | China

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JINRI CHEN: A PIONEER IN FOOD SCIENCE AND ENGINEERING 🌟

EARLY ACADEMIC PURSUITS 🎓

Jinri Chen embarked on his academic journey in Food Science and Engineering at Southwest Minzu University, where he earned his Bachelor’s degree (2004-2008). He continued his studies at Sichuan University, completing a Master’s degree in Food Science (2008-2011). His passion for research led him to pursue a Doctorate in Fermentation Engineering at Jiangnan University (2018-2022). His strong educational foundation set the stage for groundbreaking research in food chemistry, biosensors, and aptamer-based detection methods.

PROFESSIONAL ENDEAVORS 👩‍🎓

Jinri Chen is currently affiliated with Jiangsu Ocean University, Lianyungang, China. His research spans multiple aspects of food safety, biosensor development, and analytical chemistry. Throughout his academic career, he has worked on innovative detection methods for food contaminants, including antibiotics and foodborne pathogens, using aptamer-based sensors and fluorescence technology.

CONTRIBUTIONS AND RESEARCH FOCUS ON BIOSENSOR🌐

Chen's research primarily focuses on:

  • Fluorescent Aptasensors: Development of aptamer-based biosensors for detecting antibiotics, polysaccharides, and food contaminants.
  • Food Chemistry and Fermentation Engineering: Exploring advanced biochemical and analytical techniques to improve food safety and quality.
  • Nanotechnology in Food Science: Application of nanomaterials, such as quantum dots and DNA-based structures, for enhancing detection sensitivity.

IMPACT AND INFLUENCE 🌟

Jinri Chen’s work has significantly influenced the field of food safety and biosensors. His research has led to novel detection methods that offer high sensitivity and specificity in identifying harmful substances in food products. His advancements in FRET-based (Förster Resonance Energy Transfer) biosensors have been widely recognized for their applications in the food and pharmaceutical industries.

ACADEMIC CITATIONS AND PUBLICATIONS 📚

Chen has an extensive list of publications in high-impact journals, including:

  • Food Chemistry
  • Microchimica Acta
  • Analytical Biochemistry
  • Sensors and Actuators: B. Chemical
  • Journal of Agricultural and Food Chemistry

Additionally, he holds multiple patents, including:

  • CN 118465253B - A fluorescent aptasensor for detecting kanamycin content.
  • CN 202411865926.7 - A two-mode substance intelligent detection method based on bivalent aptamer.
  • CN112251493A - Detection method based on FRET and Exonuclease III-assisted recycling amplification.
  • CN113943736A - ssDNA aptamer for specific recognition of 6'-sialyllactose.

LEGACY AND FUTURE CONTRIBUTIONS 🎉

Jinri Chen’s pioneering research in biosensors and food safety has laid a strong foundation for future innovations. His work continues to shape the scientific community, paving the way for:

  • More advanced, rapid, and accurate biosensor technologies for food and environmental safety.
  • Cross-disciplinary collaborations integrating nanotechnology, bioengineering, and analytical chemistry.
  • New intellectual property developments in food science and biosensing applications.

CONCLUSION 🏆

Jinri Chen stands as a leading scientist in the field of Food Science and Engineering, with numerous contributions to biosensor technology and food safety. His continued research efforts and technological advancements ensure a lasting impact on global food security and public health.

NOTABLE PUBLICATIONS 📑

"A fluorescent aptasensor for kanamycin detection in milk, seafood and water samples using DNA-AgNCs and exonuclease I-assisted recycling amplification strategy" 

  • Authors: Dong Xu; Lei Shan; Bei Guo; Jing Wang; Qiang Huang; Shujun Wang; Fuhou Li; Shaojie Wu; Weixia
  • Journal: Food Chemistry
  • Year: 2025

"A novel dual-recognition fluorescent biosensor for sialyl-Lewisx sensitive detection" 

  • Authors: Jinri Chen; Dong Xu; Qiang Huang; Shujun Wang; Fuhou Li; Shaojie Wu; Weixia Wang; Nandi Zhou
  • Journal: Microchimica Acta
  • Year: 2024

"In vitro selection and engineering azithromycin-specific aptamers and construction of a ratiometric fluorescent aptasensor for sensitive detection of azithromycin" 

  • Authors: Tianyu Huang; Xin Chen; Jinri Chen; Yuting Zhang; Xiaoli Wang; Zhimeng Wu; Nandi Zhou
  • Journal: Sensors and Actuators
  • Year: 2024

"A FRET based ultrasensitive fluorescent aptasensor for 6′-sialyllactose detection" 

  • Authors: Jinri Chen; Yuting Zhang; Xiaoli Wang; Fuhou Li; Shaojie Wu; Weixia Wang; Nandi Zhou
  • Journal: Analytical Biochemistry
  • Year: 2024

"Screening of a Sialyllactose-Specific Aptamer and Engineering a Pair of Recognition Elements with Unique Fluorescent Characteristics for Sensitive Detection of Sialyllactose" 

  • Authors: Jinri Chen; Xin Chen; Yuting Zhang; Xiaoli Wang; Nandi Zhou
  • Journal: Journal of Agricultural and Food Chemistry
  • Year: 2023

Havva Ortabozkoyun | Gene Regulation | Best Researcher Award

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Dr. Havva Ortabozkoyun | Gene Regulation | Best Researcher Award

University of Miami Miller School of Medical / Sylvester Cancer Center | United States

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🧬 Havva Ortabozkoyun-Kara, PhD: Pioneering Epigenetics and Cancer Biology Researcher

🧑‍🎓 EARLY ACADEMIC PURSUITS

Havva Ortabozkoyun-Kara, PhD, embarked on her academic journey with a Bachelor of Science in Molecular Biology and Genetics from Middle East Technical University (METU) in Ankara, Turkey. Graduating with a stellar GPA of 3.80/4.00 in 2010, she demonstrated early on her dedication to understanding complex biological systems. Her education continued at Utrecht University in the Netherlands, where she pursued a Master of Science in Cancer Genomics and Developmental Biology. With a perfect GPA of 4.00/4.00, she excelled in this program, setting a strong foundation for her future research in cancer biology. Dr. Ortabozkoyun-Kara then achieved her PhD in Stem Cell Biology from New York University (NYU), where she graduated with a GPA of 3.89/4.00. During her doctoral studies, she delved into stem cell and developmental biology, further refining her focus on the mechanisms that drive cellular diversity and disease processes.

🧑‍🔬 PROFESSIONAL ENDEAVORS

Dr. Ortabozkoyun-Kara’s professional journey is marked by her extensive research experience in some of the most prestigious laboratories in the world. She began as a rotation student in the lab of Iannis Aifantis at NYU, where she explored the role of the ubiquitin system in cancer and stem cell function. Her doctoral research, conducted in the lab of Danny Reinberg at NYU School of Medicine, involved pioneering work on the insulation function of CTCF and the characterization of Polycomb Repressive Complex (PRC1) during differentiation. After completing her PhD, she continued her research as a Postdoctoral Fellow in the Reinberg Lab, focusing on gene regulation and the role of MAZ, CTCF, and other factors in disease processes. Currently, she holds a postdoctoral fellowship at the University of Miami Miller School of Medicine, where she is studying novel insulation factors on gene regulation during developmental and disease processes.

🔬 CONTRIBUTIONS AND RESEARCH FOCUS ON GENE REGULATION

Dr. Ortabozkoyun-Kara’s research has significantly advanced our understanding of epigenetics, stem cell biology, and cancer biology. Her work has centered on the intricate mechanisms of gene regulation, particularly the insulation functions that control the expression of Hox genes during development and in disease states. Through innovative CRISPR genetic screens and biochemical assays, she has identified key factors that cooperate with CTCF in these processes. Her research on the differences in Polycomb Repressive Complex composition during cellular differentiation has provided new insights into how these complexes contribute to the regulation of gene expression.

🌍 IMPACT AND INFLUENCE

Dr. Ortabozkoyun-Kara’s contributions to the fields of epigenetics and stem cell biology have had a profound impact on our understanding of how genetic and biochemical mechanisms lead to cellular diversity and disease. Her findings on the role of insulation factors in gene regulation have opened new avenues for research in developmental biology and cancer, influencing the direction of studies in these fields. Her expertise is recognized internationally, and she continues to collaborate with leading scientists to push the boundaries of what we know about gene regulation and its implications for human health.

📚 ACADEMIC CITATIONS

Dr. Ortabozkoyun-Kara’s work has been widely cited in the academic community, reflecting the importance of her contributions to the scientific understanding of gene regulation. Her publications in high-impact journals are frequently referenced by other researchers in the fields of molecular biology, genetics, and biochemistry. These citations underscore the relevance of her work to ongoing research and its potential to inform new therapeutic approaches for diseases linked to epigenetic regulation.

🏆 LEGACY AND FUTURE CONTRIBUTIONS

As Dr. Ortabozkoyun-Kara continues her research at the University of Miami, her legacy is one of innovation and discovery. Her future contributions are expected to further illuminate the complex mechanisms of gene regulation and their role in development and disease. With her deep expertise in epigenetics and stem cell biology, she is poised to make significant advances in the understanding and treatment of diseases driven by genetic and epigenetic alterations. Her work will undoubtedly continue to influence the fields of molecular biology and genetics for years to come, inspiring future generations of scientists.

💡 INNOVATIVE APPROACHES

Dr. Ortabozkoyun-Kara is known for her creative and methodical approaches to scientific research. She has developed novel genetic and biochemical methods that have expanded the toolkit available to researchers studying epigenetic mechanisms. Her work not only provides critical insights but also equips the scientific community with new strategies for investigating and manipulating gene expression in various biological contexts.

📑 NOTABLE PUBLICATIONS

"CRISPR and biochemical screens identify MAZ as a cofactor in CTCF-mediated insulation at Hox clusters" 

  • Authors: Havva Ortabozkoyun, Pin-Yao Huang, Hyunwoo Cho, Varun Narendra, Gary LeRoy, Edgar Gonzalez-Buendia, Jane A Skok, Aristotelis Tsirigos, Esteban O Mazzoni, Danny Reinberg
  • Journal: Nature Genetics
  • Year: 2022

"A CRISPR Screen Identifies Myc-associated Zinc Finger Protein (MAZ) as an Insulator Functioning at CTCF boundaries in Hox Clusters" 

  • Authors: Havva Ortabozkoyun-Kara, Pin-Yao Huang, Hyunwoo Cho, Varun Narendra, Gary Leroy, Jane A. Skok, Aristotelis Tsirigos, Esteban O. Mazzoni, Danny Reinberg
  • Journal: BioRxiv
  • Year: 2020

"Members of an array of zinc finger proteins specify distinct Hox chromatin boundaries"

  • Authors: Havva Ortabozkoyun, Pin-Yao Huang, Edgar Gonzalez-Buendia, Hyein Cho, Sang Kim, Aristotelis Tsirigos, Esteban Mazzoni, Danny Reinberg
  • Journal: bioRxiv
  • Year: 2023

"Members of a Family of Zinc Finger Proteins Demarcate Chromatin Boundaries at Hox Clusters during Development, Ortabozkoyun et. al"

  • Authors: Havva Ortabozkoyun, Pin-Yao Huang, Edgar Gonzalez-Buendia, Hyunwoo Cho, Sang Y Kim, Aristotelis Tsirigos, Esteban O Mazzoni, Danny Reinberg
  • Journal: Mendeley Data
  • Year: 2024

"Novel chromatin insulating activities uncovered upon eliminating known insulators in vivo"

  • Authors: Havva Ortabozkoyun, P. Huang, H. Cho, E. Mazzoni, A. Tsirigos, D. Reinberg
  • Year: 2023