Mr. Dangdang Wang | Glaucoma | Best Researcher Award
The First Affiliated Hospital of Chongqing Medical University | China
Author Profile
👁️🗨️ DANGDANG WANG — EMERGING VISION‑SCIENCE SCHOLAR
🎓 EARLY ACADEMIC PURSUITS
Dangdang Wang completed a Bachelor of Medicine (Sept 2023) at The First Clinical College of Chongqing Medical University. While still an undergraduate, he gravitated toward immune‑related disorders, setting the stage for a career studying how dysregulated immunity damages ocular tissues. His capstone projects and lab rotations introduced him to experimental glaucoma models, sparking a passion for translational eye research.
🏥 PROFESSIONAL ENDEAVORS
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Postgraduate Student (2023 – present), Department of Ophthalmology, The First Affiliated Hospital of Chongqing Medical University
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Pursues an M.Sc. in Ophthalmology (expected June 2026) under Prof. Hong Li.
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Embedded in the Chongqing Key Laboratory for the Prevention and Treatment of Major Blinding Eye Diseases and the National Clinical Research Center for Ocular Diseases (Chongqing Branch), gaining access to cutting‑edge imaging, single‑cell omics, and biostatistics cores.
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Active collaborator with neurologists, immunologists, and bioinformaticians to build multi‑omic datasets that decode optic‑nerve degeneration.
🔬 CONTRIBUTIONS AND RESEARCH FOCUS ON GLAUCOMA
GLAUCOMA PATHOGENESIS THROUGH FOUR LENSES:
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IMMUNITY – Profiling resident and infiltrating immune cells in glaucomatous optic nerves to map cytokine networks.
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INFLAMMATION – Identifying inflammasome activation patterns that tip the balance from neuroprotection to neurodegeneration.
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GENETIC SUSCEPTIBILITY – Mining GWAS and family cohorts to pinpoint risk alleles in complement and metabolic genes.
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METABOLIC DYSFUNCTION – Linking retinal‑ganglion‑cell energy failure to systemic metabolic shifts.
Notable early outputs: a conference abstract on NLRP3‑inflammasome blockade restoring axonal transport in rat glaucoma models, and a first‑author review (in press) summarizing immunometabolic crosstalk in optic‑nerve injury.
🌍 IMPACT AND INFLUENCE
Although still in training, Wang’s interdisciplinary approach is already:
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Bridging clinical and basic science by integrating patient‑derived aqueous‑humor proteomics with animal‑model data.
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Guiding therapeutic pipelines—his findings on metabolic rescue pathways are informing small‑molecule screening projects at the Chongqing Eye Institute.
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Mentoring peers in statistics workshops, boosting lab‑wide reproducibility standards.
📊 ACADEMIC CITES
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>15 citations to date across two co‑authored papers on ocular immunology (Scopus, April 2025).
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Invited speaker at the 2024 China Young Ophthalmologist Forum, where his talk on “Metabolomics‑Driven Targets for Neuroprotection” was highlighted by session chairs.
🏅 LEGACY AND FUTURE CONTRIBUTIONS
By combining immune phenotyping, metabolomics, and precision genetics, Dangdang Wang aims to:
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Define a unified “immune‑metabolic glaucoma signature” to stratify patients for personalized therapy.
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Translate bench insights to bedside trials, advancing neuroprotective agents that modulate both inflammation and energy metabolism.
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Champion open‑data initiatives within Chinese ophthalmology, accelerating nationwide collaboration.
With strong methodological skills (SPSS, R, single‑cell RNA‑seq pipelines) and a collaborative mindset, Wang is poised to become a next‑generation leader in vision science, reshaping how glaucoma is understood and treated. 🔭
📑NOTABLE PUBLICATIONS
"Potential Functions and Causal Associations of GNLY in Primary Open-Angle Glaucoma: Integration of Blood-Derived Proteome, Transcriptome, and Experimental Verification"
- Authors: D., Wang, Dangdang , Y., Pu, Yanyu , X., Gao, Xi , L., Zeng, Lihong , H., Li, Hong
- Journal: Journal of Inflammation Research
- Year: 2025