Yuhui Sun | Gene Therapy | Excellence in Research

Prof. Dr. Yuhui Sun | Gene Therapy | Excellence in Research

Huazhong University of Science and Technology | China

Prof. Dr. Yuhui Sun is a Professor at Huazhong University of Science and Technology, China. He received his Ph.D. from Shanghai Jiao Tong University and conducted postdoctoral research at the University of Cambridge in Professor Peter F. Leadlay’s group. He served as a Professor at Wuhan University before joining HUST. His research focuses on microbial natural product discovery, biosynthesis, and the development of advanced genetic and genome-editing tools, particularly CRISPR-Cas9–based base editors. Professor Sun has led eight major national and provincial research projects, published 69 SCI-indexed papers with an H-index of 25 and over 1,900 citations, authored a Springer Nature book chapter, and holds nine international and Chinese patents. He has extensive industry collaboration experience, serves on multiple international editorial boards, and is a Fellow of the Royal Society of Chemistry (UK). Internationally recognized for elucidating complex biosynthetic mechanisms and creating hybrid microbial medicines, he has also developed widely adopted genome-editing technologies shared with over 80 research groups worldwide.

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Featured Publications

Yuan MA | Gene Therapy Award | Young Scientist Award

Dr. Yuan MA | Gene Therapy Award | Young Scientist Award

Hong Kong Baptist University | China

AUTHOR PROFILE 

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EARLY ACADEMIC PURSUITS

Dr. Yuan Ma embarked on an academic journey marked by excellence and dedication. Graduating with a Bachelor's degree in Medical Chemistry from Peking University in 2013, he continued his studies at the same institution, earning a Master's degree in Medical Chemistry in 2015. His academic prowess culminated in a Ph.D. in Medical Science from Peking University's School of Medicine in 2019. These formative years laid the foundation for his subsequent professional endeavors and contributions to the field.

PROFESSIONAL ENDEAVORS

Dr. Ma's professional trajectory reflects a commitment to advancing medical science and translational research. Following the completion of his Ph.D., he embarked on a postdoctoral research fellowship at the Institute for Advancing Translational Medicine in Bone & Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University. This role provided him with valuable insights into translational research methodologies and interdisciplinary collaboration. Subsequently, he served as an Associate Research Fellow at Mengchao Hepatobiliary Hospital of Fujian Medical University, contributing to the exploration of innovative medical interventions.

CONTRIBUTIONS AND RESEARCH FOCUS ON GENE THERAPY AWARD

Throughout his academic and professional journey, Dr. Ma has focused his research efforts on areas of critical importance in medical science. His expertise encompasses nucleic acid drug discovery, precision medicine, and innovative drug development. His contributions have significantly advanced our understanding of aptamer-based translational medicine and drug discovery, particularly within the context of hepatobiliary diseases. Dr. Ma's research stands at the forefront of addressing pressing healthcare challenges, offering novel therapeutic avenues for improving patient outcomes.

IMPACT AND INFLUENCE

Dr. Ma's work has garnered recognition within the academic community and beyond, underscoring his impact and influence in the field of medical science. As the General Secretary of the Hong Kong Pharmaceutical Academy, he plays a pivotal role in shaping the future of pharmaceutical research and education. His membership in esteemed organizations such as the HKBU and IncreasePharm Joint Centre for Nucleic Acid Drug Discovery, Institute for Precision Medicine and Innovative Drug, and Guangdong-Hong Kong-Macao Greater Bay Area International Research Platform for Aptamer-based Translational Medicine and Drug Discovery underscores his standing as a thought leader in his field.

ACADEMIC CITATIONS

Dr. Ma's research findings have been disseminated widely, garnering citations from peers and scholars globally. His publications in reputable journals serve as a testament to the significance of his work and its contribution to advancing medical science. Through rigorous inquiry and meticulous experimentation, Dr. Ma has expanded the frontiers of knowledge in his domain, earning the respect and recognition of his peers.

LEGACY AND FUTURE CONTRIBUTIONS

Dr. Ma's legacy is characterized by a tireless pursuit of scientific excellence and a commitment to improving human health. His research endeavors have laid the groundwork for future breakthroughs in nucleic acid drug discovery and translational medicine. As he continues to chart new territories and push the boundaries of scientific inquiry, Dr. Ma remains dedicated to his mission of translating research findings into tangible therapeutic solutions. His future contributions hold the promise of transformative impact, further solidifying his position as a trailblazer in the field of medical science.

NOTABLE PUBLICATIONS

Nucleic acid amphiphiles: Synthesis, properties, and applications 2023(4)

Spatial imaging of glycoRNA in single cells with ARPLA 2023(10)

Chemically modified aptamers for improving binding affinity to the target proteins via enhanced non-covalent bonding 2023(11)

Binding Affinity Measurements Between DNA Aptamers and their Virus Targets Using ELONA and MST 2022(2)

Strategies for developing long-lasting therapeutic nucleic acid aptamer targeting circulating protein: The present and the future 2022(9)