Gregorio Maranon University Hospital | Spain

Author Profile

EARLY ACADEMIC PURSUITS

Since 2017, I have been dedicated to advancing the field of pharmacogenetics, beginning as a research assistant and progressing through to postdoctoral researcher at the Pharmacogenetics Laboratory of the Gregorio Marañón General University Hospital. My journey started with foundational research roles and evolved into leadership positions within various pharmacogenomic studies.

PROFESSIONAL ENDEAVORS

Starting as a research assistant, I gradually transitioned to roles as a predoctoral and postdoctoral researcher, accumulating invaluable experience and expertise in pharmacogenetics. My work has been primarily focused on pharmacogenomic studies in diverse medical areas such as colorectal cancer, multiple sclerosis, psychiatry, and intestinal inflammatory diseases.

CONTRIBUTIONS AND RESEARCH FOCUS ON PHARMACOGENMICS AND PERSONALIZED MEDICINE

Throughout my career, I have actively contributed to 21 publications in pharmacogenomics, with a particular emphasis on colorectal cancer, multiple sclerosis, psychiatry, and intestinal inflammatory diseases. Of these publications, I served as the first author for 14, showcasing my significant contributions to the field. Notably, my doctoral thesis in 2020 centered on intestinal inflammatory disease, underscoring my commitment to advancing knowledge in this area.

IMPACT AND INFLUENCE

My contributions have not gone unnoticed, as evidenced by receiving the AEFA (Spanish Clinical Laboratory Association) award for quality and innovation in 2019. Additionally, my research has been recognized through presentations at 20 national and international conferences, including 5 oral communications. I have been honored with the best oral communication award at three conferences, highlighting the impact of my work.

ACADEMIC CITES

My research has contributed to the academic discourse, with citations in various publications, further validating the significance and influence of my work in pharmacogenetics awards and related fields.

LEGACY AND FUTURE CONTRIBUTIONS

As an active member of the Spanish Society of Pharmacogenetics awards and the Spanish Association of Human Genetics, I continue to contribute to the advancement and dissemination of knowledge in these critical areas of public health. My ongoing commitment to research and collaboration ensures that my contributions will continue to shape the future of pharmacogenetics.

NOTABLE PUBLICATIONS

Polymorphisms indicating risk of inflammatory bowel disease or antigenicity to anti-TNF drugs as biomarkers of response in children 2023(3)

Single nucleotide polymorphisms in ADAM17, IL23R and SLCO1C1 genes protect against infliximab failure in adults with Crohn's disease 2023(7)

Association between HLA DNA Variants and Long-Term Response to Anti-TNF Drugs in a Spanish Pediatric Inflammatory Bowel Disease Cohort 2023(7)

Genotyping of UGT1A1*80 as an Alternative to UGT1A1*28 Genotyping in Spain 2022(5)

Pharmacogenetics to avoid adverse reactions in cardiology: Ready for implementation? 2021(4)

Jian Luo | Immunogenetics and Autoimmune Diseases | Best Researcher Award

Posted on 13/04/202413/04/2024 by PencisLeave a Comment

Dr. Jian Luo | Immunogenetics and Autoimmune Diseases | Best Researcher Award

University of Oxford | United Kingdom

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EARLY ACADEMIC PURSUITS

Jian Luo embarked on his academic journey at West China School of Medicine, Sichuan University, where he completed his Bachelor of Science in Respiratory Care in 2012. His thirst for knowledge led him to pursue further studies, culminating in a Master of Medicine from the same institution in 2015.

PROFESSIONAL ENDEAVORS

Armed with a solid foundation in respiratory medicine, Jian Luo pursued a dual degree program, earning his M.D. and Ph.D. in Respiratory Medicine from West China School of Medicine, Sichuan University, China, in 2018. His academic pursuits then took him to the prestigious University of Oxford, where he completed a Joint DPhil in Respiratory Medicine Unit, NDM Experimental Medicine, in 2018.

CONTRIBUTIONS AND RESEARCH FOCUS ON IMMUNOGENETICS AND AUTOIMMUNE DISEASES

Throughout his career, Jian Luo has focused on advancing our understanding of respiratory diseases, particularly inflammatory airway diseases such as asthma and COPD, as well as respiratory critical care medicine, including acute respiratory distress syndrome (ARDS). His research efforts have delved into various aspects of immunology and clinical medicine, with notable investigations into the mechanisms of steroid resistance in various immune cells, the role of cytokines in eosinophil priming, and the immunological signatures of COVID-19 and Immunogenetics Award, particularly in relation to asthma.

IMPACT AND INFLUENCE

Jian Luo's contributions to the field of respiratory medicine are underscored by his extensive publication record, boasting over 25 peer-reviewed papers with an impressive cumulative impact factor of 406.36. Notably, his work has been recognized in high-impact journals such as Cell, Lancet Respiratory Medicine, and the Journal of Allergy and Clinical Immunology.

ACADEMIC CITATIONS

Jian Luo's research findings have garnered attention within the scientific community, evident in the numerous citations his work has received. His studies have contributed valuable insights into the pathogenesis and treatment of respiratory diseases, earning him recognition as a leading authority in the field.

LEGACY AND FUTURE CONTRIBUTIONS

As a senior immunologist and clinician, Jian Luo's legacy extends beyond his academic achievements to his mentorship of future generations of researchers and clinicians. His continued dedication to advancing respiratory medicine promises to shape the landscape of healthcare, paving the way for improved diagnostics, treatments, and ultimately, better outcomes for patients worldwide.

NOTABLE PUBLICATIONS

Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxaemic respiratory failure: a systematic review and meta-analysis 2022(103)

Awake prone positioning for patients with COVID-19-induced acute hypoxemic respiratory failure 2022(3)

IL-1β promotes IL-17A production of ILC3s to aggravate neutrophilic airway inflammation in mice 2023(2)

The use of high-flow nasal cannula in patients with chronic obstructive pulmonary disease under exacerbation and stable phases: A systematic review and meta-analysis 2023(4)

Group 3 innate lymphoid cells secret neutrophil chemoattractants and are insensitive to glucocorticoid via aberrant GR phosphorylation 2023(1)

Spyridon Theofilopoulos | Development Neurobiology | Best Researcher Award

Posted on 26/02/202426/02/2024 by PencisLeave a Comment

Prof. Spyridon Theofilopoulos | Development Neurobiology | Best Researcher Award

Deree-The American College of Greece | Greece

AUTHOR PROFILE

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EARLY ACADEMIC PURSUITS

Spyridon Theofilopoulos embarked on his academic journey with a Bachelor of Science degree in Biochemistry from Imperial College of Science, Technology and Medicine, London, U.K. Following this, he pursued his passion for developmental neurobiology, obtaining his Ph.D. from the same institution. His doctoral research, supervised by Professor Henry F. Bradford, focused on neurotrophic factors in neurotransmitter phenotype determination and neuroprotection in the developing human and rat brain.

PROFESSIONAL ENDEAVORS

Dr. Theofilopoulos has held various academic positions internationally, demonstrating his expertise and commitment to the field. Noteworthy roles include his tenure as a Forskare (Senior Researcher/Assistant Professor) at the Karolinska Institute, Stockholm, Sweden, and as a Sêr Cymru II Rising Star fellow and Associate Professor at Swansea University Medical School, Swansea, U.K. Currently, he serves as a Professor and Instructor at the Biomedical Sciences Department of Deree-The American College of Greece, Athens, Greece.

CONTRIBUTIONS AND RESEARCH FOCUS ON DEVELOPMENT NEUROBIOLOGY

Dr. Theofilopoulos has made significant contributions to the field of developmental neurobiology, particularly in the areas of neuroprotection and neurotransmitter phenotype determination. His collaborative research with Teva Pharmaceuticals during his Ph.D. led to the development of Rasagiline, a novel compound for the treatment of Parkinson’s disease. Moreover, his work at Swansea University resulted in the establishment of the spin-off company CholesteniX Ltd, aiming to develop specific cholesterol metabolites for Amyotrophic Lateral Sclerosis therapy.

IMPACT AND INFLUENCE

Theofilopoulos's research has not only contributed to scientific advancements but has also garnered recognition and accolades. He has been invited as a speaker to numerous conferences and meetings, highlighting the impact of his work in the scientific community. Furthermore, his efforts were acknowledged with awards such as the "Outstanding Research and Innovation collaboration in Medicine, Health and Life Sciences" award in 2022.

ACADEMIC CITATIONS

Dr. Theofilopoulos's work has been cited extensively, indicating its relevance and impact in the scientific community. His publications have appeared in reputable journals, and he has served as a reviewer for various scientific publications, including Scientific Reports, eLife, and Frontiers in Cell and Developmental Biology.

LEGACY AND FUTURE CONTRIBUTIONS

Dr. Theofilopoulos's legacy lies in his dedication to advancing knowledge in developmental neurobiology and his commitment to mentoring the next generation of scientists. His research funding awards underscore the importance of his work and pave the way for future discoveries in the field. As he continues his academic journey, his contributions are expected to further shape the landscape of neuroscience research.

NOTABLE PUBLICATIONS

The Cerebrospinal Fluid Profile of Cholesterol Metabolites in Parkinson’s Disease and Their Association With Disease State and Clinical Features 2021(10)

Inhibition of 7α,26-dihydroxycholesterol biosynthesis promotes midbrain dopaminergic neuron development 2024

Mining for oxysterols in cyp7b1^−/− mouse brain and plasma: Relevance to spastic paraplegia type 5 2019(13)

24(S),25-Epoxycholesterol and cholesterol 24S-hydroxylase (CYP46A1) overexpression promote midbrain dopaminergic neurogenesis in vivo 2019(24)

Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1−/− mouse brain and plasma 2019(29)

Xiaohu Ren | Metabolic disorders and their genetic basis | Best Researcher Award

Posted on 18/02/202418/02/2024 by PencisLeave a Comment

Prof Dr. Xiaohu Ren | Metabolic disorders and their genetic basis | Best Researcher Award

Shenzhen Center for Disease Control and Prevention | China

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EARLY ACADEMIC PURSUITS:

Dr. Xiaohu Ren commenced his academic journey with a Bachelor of Science in Biological Sciences from Shenzhen University (2005-2009), followed by a Master of Science in Biochemistry and Molecular Biology (2009-2012) from the same institution. Subsequently, he pursued a Ph.D. in Health Toxicology at Southern Medical University (2012-2015), where he laid the foundation for his research expertise in the field of toxicology.

PROFESSIONAL ENDEAVORS:

Since 2015, Dr. Ren has served as an Associate Chief Physician and Assistant Researcher at the Modern Toxicology Laboratory, Shenzhen Center for Disease Control and Prevention (CDC). Prior to this, he contributed as a Postdoctoral Researcher at the Shenzhen CDC from 2015 to 2017. These roles have provided him with ample opportunities to delve into the intricacies of environmental pollutants and occupational toxicants research.

CONTRIBUTIONS AND RESEARCH FOCUS ON METABOLIC DISORDERS AND THEIR GENETIC BASIS:

Dr. Ren's research endeavors have predominantly revolved around unraveling the molecular mechanisms underlying the damage inflicted on the human body by toxic substances. His expertise spans various analytical techniques, including proteomics, untargeted lipidomics, metabolomics, and cell phenotyping. Noteworthy among his contributions are the establishment of several toxicological testing and analysis methodologies, which have significantly advanced the field.

IMPACT AND INFLUENCE:

As an active member of numerous toxicological societies and committees in China, Dr. Ren has played a pivotal role in shaping the discourse surrounding toxicology research in the country. His work has garnered attention both nationally and internationally, contributing to the broader understanding of environmental health and toxicology.

ACADEMIC CITATIONS:

Dr. Ren's research findings have been cited extensively in the academic community, attesting to the significance and relevance of his contributions to the field. His publications have enriched the scientific literature on DNA repair pathways affected by environmental toxicants and carcinogenesis, shedding light on critical aspects of human health and disease.

LEGACY AND FUTURE CONTRIBUTIONS:

With a solid foundation established through years of academic pursuit and professional engagement, Dr. Xiaohu Ren continues to be a driving force in toxicology research. His legacy encompasses a body of work that has not only advanced scientific knowledge but also contributed to the development of practical solutions for mitigating the adverse effects of environmental pollutants. Moving forward, Dr. Ren remains committed to furthering his research agenda, with a focus on addressing emerging challenges in the field and making lasting contributions to public health and environmental well-being.

Notable Publications

Co-exposure to parabens and triclosan and associations with cognitive impairment in an elderly population from Shenzhen, China 2023(2)

Long term exposure of saxitoxin induced cognitive deficits and YAP1 cytoplasmic retention 2023(2)

The relative and interactive effects of urinary multiple metals exposure on hyperuricemia among urban elderly in China 2023(4)

Association between human herpesvirus 6 (HHV-6) and cognitive function in the elderly population in Shenzhen, China 2022(3)

Zafran Khan | Tuberculosis Researcher | Editorial Board Member

Posted on 31/01/202414/02/2024 by PencisLeave a Comment

Mr. Zafran Khan | Tuberculosis | Editorial Board Member

University of Calgary | Pakisthan

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EARLY ACADEMIC PURSUITS:

ZAFRAN KHAN initiated his academic journey at the University of Swat (UOS) in Swat, Pakistan, where he pursued a Bachelor of Science (Hons) in Microbiology from 2012 to 2016. During this period, he conducted research on the "Incidence of HCV in the general population of District Swat, Pakistan," showcasing an early interest in infectious diseases and molecular biology.

PROFESSIONAL ENDEAVORS:

Following his undergraduate studies, ZAFRAN KHAN ventured into higher education at the University of Chinese Academy of Sciences (UCAS) in Beijing, China. Here, he enrolled as a Master student in Biochemistry and Molecular Biology from September 2018 to August 2019. His coursework covered diverse topics, including Genomics, Immunology, Biochemistry, and Molecular Biology, laying a solid foundation for his subsequent research pursuits.

CONTRIBUTIONS AND RESEARCH FOCUS ON TUBERCULOSIS

ZAFRAN KHAN's notable research contributions are evident during his tenure as a Master's Full-time Research Candidate at the State Key Laboratory of Respiratory Infectious Disease (GIBH) in Guangzhou, China, from August 2019 to August 2021. His primary research focus encompassed Mycobacterium tuberculosis resistance mechanisms, novel drug targets, docking, molecular dynamic simulation, and vaccine and drug designing. Noteworthy projects include the identification of resistance mechanisms associated with prothionamide and amikacin in Mycobacterium tuberculosis clinical isolates.

IMPACT AND INFLUENCE:

ZAFRAN KHAN's work holds significant implications for understanding and combating tuberculosis, a global health concern. His efforts in exploring unexplored resistance mechanisms and conducting molecular detection of anti-tubercular resistance in clinical isolates contribute to the broader scientific community's knowledge base. The impact of his research extends beyond borders, as evidenced by his involvement in international conferences and workshops.

ACADEMIC CITES:

ZAFRAN KHAN's academic journey is marked by a commitment to excellence, exemplified by his active participation in international conferences and workshops. This exposure has likely contributed to his knowledge enrichment and the incorporation of global perspectives into his research.

LEGACY AND FUTURE CONTRIBUTIONS:

ZAFRAN KHAN has established a legacy of dedication and proficiency in the field of Microbiology and Molecular Biology. His early research on HCV in Swat and subsequent work on tuberculosis resistance mechanisms showcase a commitment to addressing critical health challenges. As he progresses in his academic and research journey, ZAFRAN KHAN is poised to make further contributions to the scientific community, leaving a lasting legacy in the realm of infectious diseases and immunity.

Notable Publications

Cold stress-induced seed germination and biosynthesis of polyphenolics content in medicinally important Brassica rapa 2022(8)

Chimeric antigen receptor T cell structure, its manufacturing, and related toxicities; a comprehensive review 2022(7)

Akshay Bhuvaneswari Ramakrishnan | Bioinformatics | Young Scientist Award

Posted on 24/01/202414/02/2024 by PencisLeave a Comment

Mr. Akshay Bhuvaneswari Ramakrishnan | Bioinformatics | Young Scientist Award

Sastra University | India

Author Profile

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EARLY ACADEMIC PURSUITS

Akshay B R embarked on his academic journey by pursuing a Bachelor of Technology in Computer Science at Shanmugha Arts, Science, Technology and Research Academy, where he maintained a commendable CGPA of 7.4. Prior to this, he completed his high school education at Maharishi Vidya Mandir Senior Secondary School in Chennai, achieving a notable 72% in 2020.

PROFESSIONAL ENDEAVORS

Demonstrating a commitment to technological advancements, Akshay has been an influential Student Ambassador for Intel Since 2022. In this role, he effectively represented Intel Corporation, promoting the open-source oneAPI platform through various activities and events. Additionally, he has contributed significantly as a Research Assistant at the National Institute of Technology, engaging in research activities related to Advance Driver Assistance System (ADAS) and Brain Tumor Segmentation.

CONTRIBUTIONS AND RESEARCH FOCUS ON BIOINFORMATICS

Akshay's research focus has been on critical issues such as ADAS and Brain Tumor Segmentation. As a Research Assistant, he actively participated in literature reviews, data collection, and analysis. His contribution to developing research papers and presentations underscores his dedication to advancing knowledge in these domains.

IMPACT AND INFLUENCE

As a Clinical Data Analyst at Maruthi Hospital, Akshay applied his analytical skills to interpret clinical data, identify trends, and improve patient care. His work involved collaborating with healthcare professionals to implement data-driven solutions, showcasing a tangible impact on healthcare decision-making.

ACADEMIC CITES

Akshay's academic prowess is evident in his achievements, highlighted by his notable projects. The projects include an IoT-Based Epilepsy Detection Device, a Power BI Sales Dashboard for Zomato, and significant contributions to the field of ophthalmological disease classification and brain tumor detection using CNN architectures.

LEGACY AND FUTURE CONTRIBUTIONS

Akshay leaves a legacy of academic excellence and impactful contributions to technology and healthcare. His future contributions are anticipated to further shape the intersection of computer science, healthcare, and research, as evidenced by his continuous pursuit of knowledge and active involvement in cutting-edge projects.

Notable Publications

Optimizing brain tumor classification with hybrid CNN architecture: Balancing accuracy and efficiency through oneAPI optimization 2024