Prof. Dr. Yuhui Sun | Gene Therapy | Excellence in Research
Huazhong University of Science and Technology | China
Prof. Dr. Yuhui Sun is a Professor at Huazhong University of Science and Technology, China. He received his Ph.D. from Shanghai Jiao Tong University and conducted postdoctoral research at the University of Cambridge in Professor Peter F. Leadlay’s group. He served as a Professor at Wuhan University before joining HUST. His research focuses on microbial natural product discovery, biosynthesis, and the development of advanced genetic and genome-editing tools, particularly CRISPR-Cas9–based base editors. Professor Sun has led eight major national and provincial research projects, published 69 SCI-indexed papers with an H-index of 25 and over 1,900 citations, authored a Springer Nature book chapter, and holds nine international and Chinese patents. He has extensive industry collaboration experience, serves on multiple international editorial boards, and is a Fellow of the Royal Society of Chemistry (UK). Internationally recognized for elucidating complex biosynthetic mechanisms and creating hybrid microbial medicines, he has also developed widely adopted genome-editing technologies shared with over 80 research groups worldwide.
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Featured Publications
Engineered cytosine base editor enabling broad-scope and high-fidelity gene editing in Streptomyces
– Nature Communications, 2024 • Open Access • 11 Citations
Discovery of anti-MRSA carpatamides' congeners by heterologous expression and mechanism investigation targeting FabI and biofilm formation
– Bioorganic Chemistry, 2025 • 1 Citation
Engineering of Peptide-Inserted Base Editors with Enhanced Accuracy and Security
– Small, 2025 • Open Access • 1 Citation
Genome-Based Mining of Carpatamides I–M and Their Candidate Biosynthetic Gene Cluster
– Marine Drugs, 2024 • Open Access • 1 Citation
Structural and Functional Basis of GenB2 Isomerase Activity from Gentamicin Biosynthesis
– ACS Chemical Biology, 2024 • Open Access • 1 Citation