Xinghua Pan | Next-Generation Sequencing | Research Excellence Award

Prof. Xinghua Pan | Next-Generation Sequencing | Research Excellence Award

Macau University of Science and Technology | China

Prof. Xinghua (Victor) Pan, PhD, MD, is a distinguished scholar in single-cell technology, genome medicine, cancer biology, regenerative medicine, and multi-omics bioinformatics, currently serving as a Professor at the Precision Regenerative Medicine Research Centre (PRMRC) in the Medical Science Division of Macau University of Science and Technology (MUST), with a secondary affiliation at the State Key Laboratory of Quality Research in Chinese Medicine. A doctoral supervisor in Biomedical Science and Pharmacy programs at MUST, Dr. Pan previously served as Chairman and Professor of Biochemistry and Molecular Biology at Southern Medical University (SMU), where he founded and led the Guangdong Provincial Key Laboratory of Single Cell Technology and Application and held multiple adjunct roles across major hospitals, universities, and national laboratories. With a career spanning Yale University—where he advanced from Associate Research Scientist to Research Scientist and PI-and leadership positions in molecular genomics companies, Dr. Pan brings decades of expertise shaped by rigorous training at Southern Medical University, Fudan University, CAMS & PUMC, and Yale University, complemented by international fellowships at Peking University, Melbourne University, the Ludwig Institute, and Cold Spring Harbor Laboratory. Renowned for pioneering single-cell sequencing innovations-including multiomics, copy-number, methylome, transcriptome, telomere, and multiplexing technologies-he has applied these breakthroughs to major biomedical challenges across cancer, stem cells, organoids, aging, infectious diseases, immunology, brain disorders, and precision medicine. Dr. Pan has authored over 160 publications in high-impact journals such as Nature, PNAS, Advanced Science, Nucleic Acids Research, and Nature Communications, accumulating more than 8,500 citations and an H-index of 40, alongside 15 issued patents in the U.S. and China. His work has been supported by national and international foundations including NSFC, NIH, NSF, MOST, and leading provincial and municipal programs. A dedicated educator who has trained over 60 researchers and taught nearly 10,000 students, he also serves as an Associate Editor of Precision Clinical Medicine and Monocytomics, reviewer for more than 30 top journals, and evaluator for major grant agencies and academic degree committees. As an organizer and keynote speaker at over 100 global conferences, including co-chairing the International Conference on Single Cell and Spatial Omics (TICSSO), Dr. Pan has also held leadership roles in multiple scientific societies and earned numerous accolades such as UICC and CSHL Scholarships, PolyGenomics Fellowship, VEBLEO Fellow, Nanjing Leading Talent, Guangzhou High-Level Talent, Ganpo Distinguished Professor, and the CastUSA Single Cell Genomics Pioneer Award, solidifying his global influence in single-cell biology and precision regenerative medicine.

Profiles: Scopus | Orcid

Featured Publications

"A medium throughput approach for single cell copy number variation sequencing towards efficient application in clinics", Guanchuan Lin; Caiming Chen; Mengchang Xu; Bin Peng; Zhanying Dong; Xuewen Zhou; Jinyu Gao; Jie Yu; Bei Jia; Chen Luo et al., 2025

"Causal effects of immune cell phenotypes on the risk of autoimmune liver diseases: a bidirectional two-sample Mendelian randomization study",Hongjie Zou; Xinghe Liang; Mengqi Luo; Xinghua Pan; De-Ke Jiang., 2025

"Dynamic heterogeneity towards drug resistance in AML cells is primarily driven by epigenomic mechanism unveiled by multi-omics analysis", Yulong Zhang; Yanfang Lu; Liyao Mai; Zebin Wen; Min Dai; Siwen Xu; Xianwei Lin; Yongjian Luo; Yinbin Qiu; Yuting Chen et al., 2025

"Transcriptomics-driven exploration of genetic variation and peptide discovery in the sea anemones Anthopleura midori and Actinia equina",Han Zhang; Xinghua Pan; Chen Weigang., 2025

Vanderlei Bagnato | Host Genetics | Best Researcher Award

Dr. Vanderlei Bagnato | Host Genetics | Best Researcher Award

Texas A&M University | United States

Dr. Vanderlei Bagnato is a distinguished physicist and engineer whose illustrious career spans over four decades of groundbreaking research, academic leadership, and innovation in optics, photonics, and biomedical applications of laser technology. He earned dual B.S. degrees in Materials Engineering from the Federal University of São Carlos (UFSCAR) and in Physics from the University of São Paulo (USP), followed by an M.S. in Physics from USP and a Ph.D. in Physics from the Massachusetts Institute of Technology (MIT). Currently, he serves as a Professor of Biomedical Engineering at Texas A&M University while holding a full professorship at the Institute of Physics at São Carlos (IFSC/USP), Brazil. Over the years, Dr. Bagnato has held numerous prestigious roles, including Director of IFSC, Coordinator of the USP Innovation Agency, and long-term Coordinator of Brazil’s National Institute of Science and Technology of Optics and Photonics. His pioneering research and leadership have earned him global recognition and a multitude of honors, such as election to the U.S. National Academy of Engineering, the Willis E. Lamb Award for Laser Science and Quantum Optics, and the Robert E. Hopkins Leadership Award from Optica. He has also been honored with major national and international distinctions, including Brazil’s Admiral Álvaro Alberto Award, the CBMM Science & Technology Award, and the Commander of the National Order of Scientific Merit. Dr. Bagnato’s current research is supported by major grants such as the Texas Governor’s University Research Initiative and the Cancer Prevention and Research Institute of Texas, focusing on advanced biophotonics, laser therapy, and machine learning applications for healthcare and material analysis. Through his scientific leadership, prolific research output, and commitment to innovation, Dr. Vanderlei Bagnato continues to shape the future of optics and photonics in both fundamental science and translational biomedical engineering.

Profiles: Scopus | Google Scholar

Featured Publications

"Comparative analysis of ALA mediated sonodynamic therapy considering tumor size, light combination and ultrasound delivery in murine cutaneous melanoma", Scientific Reports, 2025.

"Unlocking BODIPY dye synthetic methodologies with 1H NMR monitoring and continuous flow techniques", Dyes and Pigments, 2025.

"Light-activated Zein–curcumin films for the photodynamic inactivation of bacterial biofilms: Continuous vs. intermittent illumination", Journal of Photochemistry and Photobiology B Biology, 2025.

"Vascular and tissue effects of photodynamic therapy in a murine cutaneous tumor model", Journal of Photochemistry and Photobiology B Biology, 2025.

"The Combined Photosensitizers in Antimicrobial Photodynamic Therapy: The Case of Methylene Blue and Photodithazine Against Klebsiella pneumoniae", International Journal of Molecular Sciences, 2025.

Yulian Ding | Molecular Basis of Genetic Disease | Best Researcher Award

Dr. Yulian Ding | Molecular Basis of Genetic Disease | Best Researcher Award

Shenzhen Institute of Advanced Technology | China

Author Profile

Scopus

Orcid ID

Google Scholar

🧬 YULIAN DING, PH.D. – PIONEER IN BIOMEDICAL ENGINEERING AND MACHINE LEARNING

EARLY ACADEMIC PURSUITS🎓

Yulian Ding embarked on her academic journey with a Bachelor of Science in Computer Science from Luoyang Normal University (2010-2014). Her passion for data science and bioinformatics was further solidified during her Master's degree in Computer Science at Shaanxi Normal University (2014-2017), where she focused on dynamic protein complex identification and essential protein identification through swarm intelligence optimization. Her research, under the guidance of Dr. Xiujuan Lei, shaped her understanding of computational biology and bioinformatics. In 2018, Yulian took her academic prowess to the next level by pursuing a Ph.D. in Biomedical Engineering at the University of Saskatchewan (2018-2022). Under the supervision of Dr. Fang-Xiang Wu, she developed advanced machine learning models to predict biomolecule-disease associations, working with miRNAs, lncRNAs, and circRNA.

PROFESSIONAL ENDEAVORS🧑‍🔬

Upon completing her Ph.D., Yulian Ding transitioned into various research roles that leveraged her expertise in both machine learning and biomedical engineering. From March 2022 to February 2023, she served as an Assistant Researcher at the Center for High Performance Computing, Shenzhen Institute of Advanced Technology, under the prestigious Chinese Academy of Sciences. Her work there focused on drug design and disease biomarker identification using machine learning techniques, contributing to major advancements in protein-ligand interaction prediction. Concurrently, Yulian completed a Postdoctoral Fellowship at the University of Saskatchewan’s College of Medicine and Division of Biomedical Engineering. She specialized in bio-data analytics, working on clinical data, particularly in identifying cirRNA biomarkers for cancer.

CONTRIBUTIONS AND RESEARCH FOCUS ON MOLECULAR BASIS OF GENETIC DISEASE🔬

Yulian Ding’s research focuses on biomedical informatics, particularly at the intersection of machine learning and biomolecular interaction. Her key contributions lie in:

  • Developing novel machine learning models for predicting disease-associated biomolecules, including miRNAs, lncRNAs, and circRNA.
  • Drug design and disease biomarker discovery, particularly through the integration of machine learning in protein-ligand interactions.
  • Enhancing the understanding of bio-data analytics in oncology, utilizing vast datasets to identify crucial molecular targets for treatment.

IMPACT AND INFLUENCE🌍

Ding's work has had significant implications in precision medicine, especially in the early detection of diseases through biomarker identification. Her research on biomolecule-disease associations and the use of machine learning for drug discovery has positioned her as a rising leader in the biomedical engineering field. Her collaboration with leading scientists and institutions, including her postdoctoral work, has influenced both academic research and practical applications in biotechnology.

ACADEMIC CITES📚

Yulian Ding has been recognized for her academic excellence through numerous prestigious awards:

  • Dr. Victor A. Pollak and Mirka B. Pollak Scholarship (2021, University of Saskatchewan)
  • Russell (Russ) William Haid Memorial Award (2020, University of Saskatchewan)
  • China’s National Scholarship for Graduate Students (2017)
  • China’s National Second Prize of Lanqiao Cup Software Design Competition (2014)
  • ACM Programming Competition Silver Medal (2014)

Her work has been published in leading academic journals and recognized by international peers in the fields of bioinformatics and computational biology. As a journal reviewer for notable journals like Neurocomputing, Knowledge-Based Systems, and PLOS Computational Biology, she has contributed to shaping future research trends.

LEGACY AND FUTURE CONTRIBUTIONS🔮

Yulian Ding's legacy is deeply intertwined with her pioneering work in biomedical engineering. By harnessing the power of machine learning, she has opened new avenues for disease diagnosis and drug development. Her future endeavors are poised to push the boundaries of biomedical innovation, with a continued focus on applying computational intelligence to solve biomedical challenges. Through ongoing research and collaboration, Yulian will undoubtedly remain at the forefront of biomedical science, contributing to innovations that bridge the gap between computation and medicine.

 FINAL THOUGHTS🏅

Yulian Ding's academic journey, professional achievements, and innovative research establish her as a significant figure in biomedical engineering. Her work continues to make impactful contributions to precision medicine and biomedical informatics, shaping the future of healthcare through cutting-edge machine learning applications.

NOTABLE PUBLICATIONS📑

"MRDPDA: A multi-Laplacian regularized deepFM model for predicting piRNA-disease associations" 

  • Authors: Liu, Y. , Zhang, F. , Ding, Y. , Li, J. , Wu, F.-X.
  • Journal: Cellular and Molecular Medicine
  • Year: 2024

"P4PC: A Portal for Bioinformatics Resources of piRNAs and circRNAs" 

  • Authors: Liu, Y., Li, R., Ding, Y., Hei, X., Wu, F.-X.
  • Journal: Bioinformatics
  • Year: 2024

"Negative sample selection for miRNA-disease association prediction models" 

  • Authors: Ding, Y. , Wang, F. , Zhang, Y. , Wu, F.-X.
  • Journal: Machine Learning Methods for Multi-Omics Data Integration
  • Year: 2023

"Biomarker Identification via a Factorization Machine-Based Neural Network With Binary Pairwise Encoding" 

  • Authors: Ding, Y. , Lei, X. , Liao, B. , Wu, F.-X
  • Journal: IEEE/ACM Transactions on Computational Biology and Bioinformatics
  • Year: 2023

"MLRDFM: a multi-view Laplacian regularized DeepFM model for predicting miRNA-disease associations" 

  • Authors: Ding, Y. , Lei, X. , Liao, B. , Wu, F.-X
  • Journal: Briefings in Bioinformatics
  • Year: 2022